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29766 TMOD3

29766

TMOD3

tropomodulin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition tropomodulin 3

研究结论

Date Results Publications
2020-02-01 11:27:00 These findings reveal that Tmod3 enhances aggressive behavior of hepatocellular carcinoma (HCC) both in vitro and in vivo by interacting with EFGR and by activating the PI3K-AKT signaling pathway. 31313392
2019-06-29 13:17:00 TMOD3 expression was found to be elevated in liver cancer cells and tissues. In the in vitro experiments, liver cancer cell proliferation, invasion and migration were inhibited by TMOD3 knockdown and promoted by ectopic expression of TMOD3. TMOD3 overexpression activated MAPK/ERK signaling and increased the levels of other targets of this pathway. 30864730
2016-12-24 11:13:00 study has identified several new proteins like RHOC, DLG5, UGDH, TMOD3 in addition to known chemoresistance associated proteins in non-small cell lung carcinoma. 26898345
2012-05-19 10:47:00 investigation of biomarkers for early diagnosis of endometriosis: Data suggest that TMOD3, tropomyosin 3, and stomatin-like protein 2 are autoantigens present in blood of women with endometriosis; immunodominant epitopes were identified. 22158085
2010-01-21 00:00:00 findings show that the pointed-end capping protein Tmod3 contributes to epithelial cell shape within confluent monolayers of polarized epithelial cells 17928307

名称对应

Type IDs
Synonymous UTMOD
Gene
UniProtKB-ID: TMOD3_HUMAN
UniprotKB: Q9NYL9
UniParc: UPI0000137082
EMBL: BC020542, AK312569, AL137543, AF177171, AF237631
Ensembl: ENSG00000138594
KO: hsa:29766
Nucleutide sequences
EMBL-CDS: BAG35464.1, CAB70801.1, AAF31670.1, AAH20542.1, AAF45299.1
Ensembl_TRS: ENST00000308580
Protein sequencees
Ensembl_PRO: ENSP00000308753
RefSeq: XP_016877577.1, XP_016877576.1, NP_055362.1
Others
UniRef100: UniRef100_Q9NYL9
UniRef90: UniRef90_Q9NYL9
UniRef50: UniRef50_Q9NYL9
UniGene: Hs.4998
CCDS: CCDS10145.1

全选

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研究热度

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