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2975 GTF3C1

2975

GTF3C1

general transcription factor IIIC subunit 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition general transcription factor IIIC subunit 1

研究结论

Date Results Publications
2014-03-22 11:40:00 These findings reveal a novel and essential regulatory function of both SINEs and TFIIIC in mediating gene relocation and transcription 23966877
2010-08-16 11:11:00 Maf1, a repressor that binds and inhibits pol III, is phosphorylated in a mTOR-dependent manner both in vitro and in vivo at serine 75, a site that contributes to its function as a transcriptional inhibitor. 20543138
2010-01-21 00:00:00 The partial purification of pol III transcription factors from PE and EC cells revealed that TFIIIC2 activity could be purified from both cell types, whereas TFIIIC1 activity was dramatically reduced in extracts from PE cells. 11741993
2010-01-21 00:00:00 TFIIIC is composed of six subunits, five of which are conserved in humans. We report the identification, molecular cloning, and characterization of the sixth subunit of human TFIIIC, TFIIIC35 17409385
2010-01-21 00:00:00 Results identify TFIIIC as a recruitment factor for p300 and thus may have important implications for the emerging concept that tRNA genes or TFIIIC binding sites act as chromatin barriers to prohibit spreading of silenced heterochromatin domains. 18644873

名称对应

Type IDs
Synonymous TFIIIC, TFIIIC220, TFIIICalpha
Gene
UniProtKB-ID: TF3C1_HUMAN
UniprotKB: Q12789
UniParc: UPI0001838877, UPI00001FF123
EMBL: U02619, AC025275, BC044857, BC137229, AC002303, U06485, AC002551
Ensembl: ENSG00000077235
KO: hsa:2975
Nucleutide sequences
EMBL-CDS: AAA17985.1, AAB67637.1, AAH44857.1, AAI37230.1, AAA85638.1, AAC05811.1
Ensembl_TRS: ENST00000561623, ENST00000356183
Protein sequencees
Ensembl_PRO: ENSP00000455417, ENSP00000348510
RefSeq: NP_001511.2, NP_001273171.1, XP_016878677.1
Others
UniRef100: UniRef100_Q12789
UniRef90: UniRef90_Q12789
UniRef50: UniRef50_Q12789
UniGene: Hs.371718
CCDS: CCDS66988.1, CCDS32414.1

全选

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