| Type | Description |
|---|---|
| Definition | glutamate cysteine ligase, modifier subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 12:22:00 | Study determined the effects of troxerutin on cognitive deficits and glutamate cysteine ligase subunits (GCLM and GCLC) in the hippocampus of streptozotocin-induced type 1 diabetes mellitus rat: troxerutin alleviates oxidative stress and promotes learning potential in STZ-induced diabetic rats likely through GCL mechanisms, especially that of GCLC. | 27998794 |
| 2015-01-03 10:42:00 | Upregulation of both GCLC and GLCM mRNA levels in response to cysteine deprivation was dependent on new protein synthesis. | 24557597 |
| 2010-10-23 11:04:00 | Thus, the present results indicate that the vitamin E-induced regulation of SRD5A1 and GCLM in rat liver is not directly mediated by changes in promoter DNA methylation. | 20447326 |
| 2010-01-21 00:00:00 | gonadotropins regulate follicular GCL expression in a follicle stage-dependent manner and in a GCL subunit-dependent manner | 15811874 |
| 2010-01-21 00:00:00 | the catalytic efficiency of rat GCL is increased by holoenzyme formation and the first demonstration of differential up-regulation of the GCL subunits in response to cysteine deprivation | 16137247 |
| Type | IDs |
|---|---|
| Synonymous | Glclr |
| Gene |
UniProtKB-ID:
GSH0_RAT
UniprotKB:
P48508
UniParc:
UPI000012BBA8
EMBL:
L22191,
S65555,
BC078867
Ensembl:
ENSRNOG00000013409
KO:
rno:29739
|
| Nucleutide sequences |
EMBL-CDS:
AAA41543.1,
AAH78867.1,
AAB28225.1
Ensembl_TRS:
ENSRNOT00000018343
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000018343
RefSeq:
NP_059001.1
|
| Others |
UniRef100:
UniRef100_P48508
UniRef90:
UniRef90_P48508
UniRef50:
UniRef50_P48508
UniGene:
Rn.2460
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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