| Type | Description |
|---|---|
| Definition | HtrA serine peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 12:13:00 | The inhibition of Omi/HtrA2 by UCF-101 leads to neuroprotection by inhibiting the cytosolic translocation of Omi/HtrA2 and antagonizing the caspase-dependent apoptosis pathway. | 30286467 |
| 2018-10-20 10:34:00 | Local high expression of Apo-J in the peripheral regions may play a neuroprotective role by inhibiting apoptosis via the Omi/HtrA2 pathway after hemorrhage | 29581019 |
| 2018-03-24 10:47:00 | Omi/HtrA2-HAX-1 chain played a significant role in mitochondrial homeostasis. | 27998213 |
| 2014-12-20 10:51:00 | Findings suggest that upregulated HtrA2 played a role in Mn-induced neuronal death in brain striatum | 24657776 |
| 2014-04-19 11:52:00 | HtrA2 might exert an important function in regulating caspase-dependent neuronal apoptosis through interacting with XIAP following intracerebral hemorrhage. | 23413020 |
| Type | IDs |
|---|---|
| Synonymous | Prss25 |
| Gene |
UniProtKB-ID:
B0BNB9_RAT
UniprotKB:
B0BNB9
UniParc:
UPI00001CF4FA
EMBL:
BC158760,
AC130866,
CH473957
Ensembl:
ENSRNOG00000022448
KO:
rno:297376
|
| Nucleutide sequences |
EMBL-CDS:
EDL91109.1,
AAI58761.1
Gene_ORFName:
rCG_56292
Ensembl_TRS:
ENSRNOT00000037333
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000030076
RefSeq:
NP_001100069.1
|
| Others |
UniRef100:
UniRef100_B0BNB9
UniRef90:
UniRef90_Q9JIY5
UniRef50:
UniRef50_O43464-3
UniGene:
Rn.107325
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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