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29718 Kcnj10

29718

Kcnj10

potassium voltage-gated channel subfamily J member 10

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition potassium voltage-gated channel subfamily J member 10

研究结论

Date Results Publications
2019-06-24 08:00:00 he down-regulation of Kir4.1 channels in astrocytes is involved in audiogenic epileptogenesis caused by Lgi1 mutation. 30813600
2018-08-04 10:20:00 H3K9me2 and G9a are sensitive to epileptic seizure activity during the acute phase of epilepsy and can affect the transcriptional regulation of the Kcnj10 (Kir4.1) channel. 29115470
2018-05-26 10:05:00 studies suggest that AGE-modification of laminin is detrimental to Kir4.1 channels. By studying the role of AGEs in Kir4.1 channels we have identified a novel mechanism of Muller cell dysfunction and its subsequent involvement in Diabetic retinopathy. 29474462
2017-09-16 11:52:00 IL-1beta promotes the proliferation of cultured astrocytes by influencing the expression of Kir4.1. 28395711
2017-07-22 10:23:00 Kir4.1 channels possess a diurnal rhythm, and this rhythm is dampened with diabetes, thereby suggesting that the increase in TNF-alpha is detrimental to normal Kir4.1 rhythm and expression. 28460049

名称对应

Type IDs
Gene
UniProtKB-ID: KCJ10_RAT
UniprotKB: P49655
UniParc: UPI000012D8A7
EMBL: X86818, U27558, X83585
KO: rno:29718
Nucleutide sequences
EMBL-CDS: CAA58568.1, AAA87811.1, CAA60501.1
Protein sequencees
RefSeq: XP_008767959.1, NP_113790.2, XP_017454263.1, XP_017454264.1
Others
UniRef100: UniRef100_P49655
UniRef90: UniRef90_Q9JM63
UniRef50: UniRef50_Q9JM63
UniGene: Rn.10196

全选

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研究热度

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