| Type | Description |
|---|---|
| Definition | calcium voltage-gated channel subunit alpha1 D |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:07:00 | Cdk5 phosphorylates CaV1.3 channels and regulates GABAA-mediated miniature inhibitory post-synaptic currents in striato-nigral terminals. | 31983427 |
| 2020-09-19 16:27:00 | CaV1.2 and CaV1.3 voltage-gated L-type Ca2+ channels in rat white fat adipocytes. | 31770099 |
| 2018-04-28 10:46:00 | Study have showned a significant effect of the autism-associated mutation A760G on the gating of CaV1.3 such that channel activation is significantly left-shifted, Ca(2+)-dependent inactivation is decreased, and deactivation is slowed, resulting in excess Ca2+ entry. However, these effects are mitigated by an increase in voltage-dependent inactivation. Also, A760G mutation differentially affects CaV1.3 splice variants. | 27255217 |
| 2018-04-28 10:45:00 | L-type channels in insulin-secreting cells are directly targeted by cGMP signaling through PKG. | 28807144 |
| 2018-03-17 12:16:00 | In addition, single-molecule localization microscopy revealed striking clusters of CaV1.3 channels surrounding clusters of BK channels and forming a multi-channel complex both in a heterologous system and in rat hippocampal and sympathetic neurons. | 28665272 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CAC1D_RAT
UniprotKB:
P27732
UniParc:
UPI000002A5B9,
UPI000002A5B1,
UPI000002A5B7,
UPI000002A5B6,
UPI000002A5B4,
UPI000002A5B3,
UPI0000127274,
UPI000002A5BA,
UPI000002A5B5,
UPI000002A5B2,
UPI000002A5B8
EMBL:
M99221,
U14005,
U49127,
D38102,
D38101,
U31772,
U49126,
U49128,
M57682
KO:
rno:29716
|
| Nucleutide sequences |
EMBL-CDS:
AAB61635.1,
BAA07282.1,
AAB61634.1,
AAB60515.1,
AAB61636.1,
AAA42015.1,
AAA40895.1,
BAA07283.1,
AAA89156.1
|
| Protein sequencees |
RefSeq:
XP_006252657.1,
XP_017455544.1,
XP_017455556.1,
XP_017455557.1,
NP_001376154.1,
XP_017455559.1,
XP_017455558.1,
XP_006252652.1,
XP_017455555.1,
XP_006252656.1,
XP_006252659.1,
XP_017455547.1,
XP_017455550.1,
XP_017455554.1,
XP_017455549.1,
XP_008769214.1,
XP_017455552.1,
NP_058994.1,
XP_017455548.1,
XP_017455553.1,
XP_017455551.1,
XP_017455545.1,
XP_008769213.1,
XP_017455546.1
|
| Others |
UniRef100:
UniRef100_P27732
UniRef90:
UniRef90_P27732
UniRef50:
UniRef50_P27732
UniGene:
Rn.89671
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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