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29709 Gabrg2

29709

Gabrg2

gamma-aminobutyric acid type A receptor gamma 2 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition gamma-aminobutyric acid type A receptor gamma 2 subunit

研究结论

Date Results Publications
2014-12-27 12:58:00 RNF34 regulates postsynaptic gamma2-GABAAR clustering and GABAergic synaptic innervation by interacting with and ubiquitinating the gamma2-GABAAR subunit promoting GABAAR degradation 25193658
2014-08-23 11:54:00 This study demonistrated that Gabrg2 receptors are located in cholinergic terminals in the nucleus pontis oralis of the rat. 24141149
2014-04-26 12:33:00 This study provides evidence that alpha1F64, a key aromatic residue at the GABA binding site, is involved in both the binding and gating properties of alpha1beta1gamma2 receptors. 24573278
2014-04-26 11:01:00 Switching the intracellular domains of the gamma2 and gamma1 subunits substantiated this inference. Because this region determines post-synaptic localization, we hypothesize that GABAARs containing gamma1 and gamma2 use different mechanisms for synaptic clustering. 24425869
2013-05-18 12:02:00 Data indicate there was an inverse correlation between depressive-like behaviors and GABA(A)R alpha1 subunit mRNA expression in the right hemisphere in female and progesterone decreased the GABA(A)R gamma2 mRNA expression only in the left hemisphere of male. 22806324

名称对应

Type IDs
Gene
UniProtKB-ID: GBRG2_RAT, Q6PW52_RAT
UniprotKB: P18508, Q6PW52
UniParc: UPI000012AFCA, UPI000021D768
EMBL: L08497, CH473948, AC136540, AY574252
Ensembl: ENSRNOG00000003241
KO: rno:29709
Nucleutide sequences
EMBL-CDS: AAC42036.1, EDM04119.1, AAS90348.1
Gene_ORFName: rCG_33820
Ensembl_TRS: ENSRNOT00000004619, ENSRNOT00000082445
Protein sequencees
Ensembl_PRO: ENSRNOP00000004619, ENSRNOP00000072234
RefSeq: XP_006246187.1, NP_899156.1
Others
UniRef100: UniRef100_Q6PW52, UniRef100_P18508
UniRef90: UniRef90_P22723, UniRef90_P18508
UniRef50: UniRef50_P22723, UniRef50_P18507
UniGene: Rn.230132

全选

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