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29680 Cyp11a1

29680

Cyp11a1

cytochrome P450, family 11, subfamily a, polypeptide 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cytochrome P450, family 11, subfamily a, polypeptide 1

研究结论

Date Results Publications
2020-07-25 12:52:00 these steroidogenic enzymes within the Leydig cells, including steroidogenic acute regulatory protein (StAR), cholesterol side-chain cleavage cytochrome P450 (P450scc) and 3beta-hydroxysteroid dehydrogenase (3beta-HSD), were down-regulated. 30884106
2017-07-01 10:16:00 epigenetic changes such as histone modifications and chromatin remodeling occurred in the promoter region in granulosa cellss undergoing luteinization during ovulation 27428926
2015-01-03 10:38:00 In vivod-Asp administration induced serum LH release, causing indirect increase of androstenedione and testosterone levels by enhancing StAR, cytochrome P450 cholesterol side-chain cleavage enzyme and 3beta-hydroxysteroid dehydrogenase isomerases mRNA levels 24713504
2014-06-14 13:04:00 These results suggest that P450scc overexpression and the resultant increase of 3alpha,5alpha-THP-positive cells in the ventral tegmental area reduces ethanol reinforcement. 24760842
2013-06-29 12:46:00 Leptin, which inhibits the ovulatory process, caused a significant reduction in the ovarian expression of P450scc without changes in StAR or 3betaHSD. 23332974

名称对应

Type IDs
Synonymous Cyp11a, Cypxia1, P450(scc), P450scc
Gene
UniProtKB-ID: CP11A_RAT
UniprotKB: P14137
UniParc: UPI0000126BA5
EMBL: BC089100, M63133, M63128, M22615, M63130, M63131, M63132, M63127, M63125, M63126, M63129, J05156
KO: rno:29680
Nucleutide sequences
EMBL-CDS: AAA40989.1, AAA40958.1, AAA62267.1, AAH89100.1
Protein sequencees
RefSeq: NP_058982.1
Others
UniRef100: UniRef100_P14137
UniRef90: UniRef90_P14137
UniRef50: UniRef50_P14137
UniGene: Rn.1401

全选

研究热度

研究结论
热点单位
排名 科研单位 文献
1

Indian Institute of Technology Roorkee

4
2

Weizmann Institute of Science

2
3

Institute of Zoology

2
4

Baylor College of Medicine

2
5

University of Sherbrooke

2
热点人员
排名 研究人员 文献
1

Vikas Kumar

4
2

Partha Roy

4
3

Vamsi K Mootha

2
4

Walter L Miller

2
5

T Lin

2
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