| Type | Description |
|---|---|
| Definition | purinergic receptor P2X 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 12:21:00 | Overexpression of P2X4R in Schwann cells promotes motor and sensory recovery after nerve injury. | 30306657 |
| 2019-04-27 11:34:00 | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and | 29973381 |
| 2019-03-23 12:19:00 | intrathecal or ganglionar (L5-DRG) administration of a novel P2X4R antagonist (PSB-15417) or intrathecal administration of oligodeoxynucleotides (ODN)-antisense against the P2X4R reversed diabetes-induced neuropathic mechanical hyperalgesia. The dorsal root ganglia of the diabetic neuropathic rats showed an increase in P2X4R expression. | 30537520 |
| 2019-03-02 10:07:00 | neuropathic pain is related to the expression of the P2X4 receptor in the L4-5 dorsal root ganglion | 30507759 |
| 2019-02-16 12:22:00 | The importance of this movement was confirmed by demonstrating that substitution introducing positive charge present in the CRH of the hP2X1R causes sensitivity at the normally insensitive rat P2X4R. This study provides a template for developing P2XR subtype selectivity based on the differences among the mammalian subunits around the orthosteric P2XR-binding site and the CRH. | 29997254 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
P2RX4_RAT
UniprotKB:
P51577
UniParc:
UPI0000130FF7
EMBL:
X87763,
BC078792,
X91200,
X93565,
U32497,
U47031
Ensembl:
ENSRNOG00000001300
KO:
rno:29659
|
| Nucleutide sequences |
EMBL-CDS:
CAA61037.1,
AAC52380.1,
AAH78792.1,
CAA62607.1,
AAA99777.1,
CAA63778.1
Ensembl_TRS:
ENSRNOT00000001752
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001752
RefSeq:
NP_113782.2
|
| Others |
UniRef100:
UniRef100_P51577
UniRef90:
UniRef90_P51577
UniRef50:
UniRef50_P51577
UniGene:
Rn.7176
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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