| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase domain 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 12:09:00 | Abeta1-42 oligomers trigger an aberrant plasticity mechanism according to which Abeta1-42 oligomers can downregulate Abeta generation through the modulation of ADAM10 synaptic availability. | 30989630 |
| 2019-04-27 11:22:00 | This study demonstrates the involvement of ADAM10 and PI3K/Akt signaling in mediating RLX-induced Notch-1 activation. | 29180109 |
| 2019-02-02 12:07:00 | our results indicate a positive role of PLD1 in synaptogenesis by inhibiting the ADAM10 mediated N-cadherin cleavage and provide new therapeutic clues for some neurological diseases. | 28729535 |
| 2018-12-22 12:33:00 | In this study, we demonstrated that ADAM10 plays an important role in PAX2-induced EMT in the renal tubular epithelia | 30117015 |
| 2018-06-02 11:00:00 | Our findings indicate that neuron-derived ADAM10 production stimulates peripheral nerve injury-induced neuropathic pain by cleaving E-cadherin in satellite glial cells. | 28169407 |
| Type | IDs |
|---|---|
| Synonymous | MADM |
| Gene |
UniProtKB-ID:
ADA10_RAT
UniprotKB:
Q10743
UniParc:
UPI0000DA3097
EMBL:
AABR07070611,
AABR07070609,
Z48444,
CH474041,
AABR07070612,
AABR07070614,
AABR07070610,
AABR07070613
Ensembl:
ENSRNOG00000054257
KO:
rno:29650
|
| Nucleutide sequences |
EMBL-CDS:
EDL84174.1,
CAA88359.1
Ensembl_TRS:
ENSRNOT00000083255
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073306
RefSeq:
XP_006243431.1,
NP_062127.1,
XP_017451003.1
|
| Others |
UniRef100:
UniRef100_Q10743
UniRef90:
UniRef90_Q10743
UniRef50:
UniRef50_O14672
UniGene:
Rn.42924
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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