| Type | Description |
|---|---|
| Definition | general transcription factor IIH subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Structural and dynamical insights into the PH domain of p62 in human TFIIH. | 33211877 |
| 2021-01-16 16:00:00 | The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair. | 33166411 |
| 2019-10-26 10:31:00 | GTF2H1 is a direct transcriptional target of MITF. | 30651597 |
| 2019-04-06 12:26:00 | The results unveil a tight connection between TFIIH and KAT2A that controls higher-order chromatin structure and gene expression and provide new insights into transcriptional dysregulation in a cancer-prone DNA repair-deficient disorder, Xeroderma Pigmentosum B-Cockayne Syndrome. | 30894545 |
| 2019-01-26 11:42:00 | The sensitivity of SWI/SNF-deficient cells to DNA damage induced by UV irradiation and cisplatin treatment depends on GTF2H1 levels. | 30287812 |
| Type | IDs |
|---|---|
| Synonymous | BTF2, P62, TFB1, TFIIH |
| Gene |
UniProtKB-ID:
TF2H1_HUMAN,
A0A384MTQ8_HUMAN
UniprotKB:
P32780,
A0A384MTQ8
UniParc:
UPI0000136C8A,
UPI00004A2801
EMBL:
AY163770,
AK027003,
AC084117,
AK127204,
M95809,
BC000365,
CH471064,
GQ891448,
BC004452,
AJ131959,
CR457368
Ensembl:
ENSG00000110768,
ENSG00000288114
KO:
hsa:2965
|
| Nucleutide sequences |
EMBL-CDS:
EAW68401.1,
CAG33649.1,
AAH04452.1,
BAB15621.1,
EAW68400.1,
AAH00365.1,
CAC00685.1,
EAW68399.1,
AAN46740.1,
AAA58399.1,
BAG54452.1,
ADO22310.1
Ensembl_TRS:
ENST00000672845,
ENST00000453096,
ENST00000265963,
ENST00000672827,
ENST00000672527,
ENST00000534641
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265963,
ENSP00000500852,
ENSP00000500178,
ENSP00000435375,
ENSP00000393638,
ENSP00000500357
RefSeq:
XP_006718271.1,
XP_024304226.1,
NP_001135779.1,
NP_005307.1,
XP_024304225.1
|
| Others |
UniRef100:
UniRef100_P32780
UniRef90:
UniRef90_P32780
UniRef50:
UniRef50_P32780
UniGene:
Hs.577202
CCDS:
CCDS7838.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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