| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, non-receptor type 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:34:00 | Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development. | 32707818 |
| 2019-03-02 12:07:00 | activation of synaptic NMDAR by bicuculline or D-serine results in the ubiquitination and proteasomal degradation of STEP61, and increased surface localization of GluN1/GluN2B receptors. | 28466270 |
| 2018-05-19 10:24:00 | findings suggest that Src and STEP recruitment is contingent on differing intracellular Ca(2+) dynamics that dictate whether NMDAR function is augmented or depressed following M1R stimulation | 27857196 |
| 2016-12-17 11:22:00 | It is involved in the etiology of several age-associated neurologic disorders linked to oxidative stress and is also known to play a role in neuroprotection by modulating glutamatergic transmission. | 27103516 |
| 2016-07-16 10:59:00 | activity-dependent regulation of STEP61 and its substrates GluN2B and GluA2 may contribute to homeostatic stabilization of excitatory synapses. | 26391783 |
| Type | IDs |
|---|---|
| Synonymous | STEP |
| Gene |
UniProtKB-ID:
PTN5_RAT,
A0A0G2QC31_RAT
UniprotKB:
P35234,
A0A0G2QC31
UniParc:
UPI0003D0FA76,
UPI0000132969
EMBL:
S49400,
AABR07003275,
AABR07003276,
AABR07003274
Ensembl:
ENSRNOG00000013981
KO:
rno:29644
|
| Nucleutide sequences |
EMBL-CDS:
AAB19491.1
Ensembl_TRS:
ENSRNOT00000018860
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000018860
RefSeq:
XP_008757568.1,
XP_006229319.1,
XP_006229316.1,
NP_062126.4,
XP_006229315.1,
XP_006229317.1,
XP_006229314.1,
XP_017444553.1
|
| Others |
UniRef100:
UniRef100_A0A0G2QC31,
UniRef100_P35234
UniRef90:
UniRef90_P35234,
UniRef90_A0A0G2QC31
UniRef50:
UniRef50_P35234,
UniRef50_P54829
UniGene:
Rn.10618
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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