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29629 Gria4

29629

Gria4

glutamate ionotropic receptor AMPA type subunit 4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glutamate ionotropic receptor AMPA type subunit 4

研究结论

Date Results Publications
2018-01-06 10:12:00 Hippocampal GluA2 and GluA4 protein but not corresponding mRNA and promoter methylation levels are modulated at retrieval in spatial learning of the rat. 27714514
2017-07-15 12:12:00 Data show that activation leads to insertion of GluA4 to synaptic sites with initially weak or silent AMPAR-mediated transmission. This suggests that the GluA4-mediated activation of silent synapses is a critical mechanism facilitating the functional maturation of glutamatergic circuitry during the critical period of experience-dependent fine-tuning. 27157711
2013-11-16 10:07:00 The results of this study support the local translation of GluA1-4 mRNAs in dendrites of hippocampal pyramidal cells and CA1 interneurons but not in granule cells of the dentate gyrus. 23296627
2013-06-01 10:39:00 Here we examine whether hypoxia in the developing retina would cause activation of the AMPA GluRs and increase in Ca(2+) influx into retinal ganglion cells (RGCs) that might ultimately lead to their death. 23375774
2011-12-06 13:12:00 Similar to clozapine, JL 13 does not alter levels of NMDA and AMPA receptors in hippocampus and entorhinal cortex. 17873364

名称对应

Type IDs
Synonymous GluA4, GluR-D, GluR4
Gene
UniProtKB-ID: GRIA4_RAT, G3V6W1_RAT, Q566D4_RAT, A0A0G2JU28_RAT
UniprotKB: P19493, G3V6W1, Q566D4, A0A0G2JU28
UniParc: UPI000050406A, UPI000012B7C7, UPI000002AA94, UPI000002AA93, UPI000025045F, UPI000050406B
EMBL: AABR07068921, AC107267, M38063, S94371, M36421, AABR07068920, AC128948, AABR07068924, AABR07068923, BC093608, CH474089, AABR07068919, AABR07068922, AABR07068925, M85037, AABR07073357
Ensembl: ENSRNOG00000006957
KO: rno:29629
Nucleutide sequences
EMBL-CDS: AAA41242.1, AAB21763.1, AAA63481.1, AAA41246.1, EDL85231.1, AAH93608.1, EDL85230.1
Gene_ORFName: rCG_24522, rCG_24522
Ensembl_TRS: ENSRNOT00000009542, ENSRNOT00000078765, ENSRNOT00000081171
Protein sequencees
Ensembl_PRO: ENSRNOP00000009542, ENSRNOP00000068876, ENSRNOP00000068940
RefSeq: XP_017451002.1, NP_001106656.1, NP_058959.2, NP_001106655.1, XP_017450999.1, XP_017451000.1, XP_017451001.1
Others
UniRef100: UniRef100_A0A0G2JU28, UniRef100_Q566D4, UniRef100_G3V6W1, UniRef100_P19493
UniRef90: UniRef90_P48058-2, UniRef90_P19493
UniRef50: UniRef50_P48058-2, UniRef50_P19493
UniGene: Rn.10938

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