Type | Description |
---|---|
Definition | glutamate ionotropic receptor AMPA type subunit 3 |
Date | Results | Publications |
---|---|---|
2019-07-20 10:13:00 | Study shows that oxygen and glucose deprivation (OGD) causes endocytosis, lysosomal targeting and consequent degradation of GluA2- and GluA3-containing AMPARs, and that PICK1 is required for both OGD-induced GluA2 endocytosis and lysosomal sorting. GluA1-containing AMPARs resist OGD-induced endocytosis and PICK1 binding to the endocytic adaptor AP2 is enhanced by OGD in hippocampal, but not cortical neurons. | 28951554 |
2017-10-07 12:22:00 | results lead to a model of cooperative activation of mGluRs that provides a framework for understanding how class C GPCRs couple extracellular binding to dimer reorganization and G protein activation. | 27641494 |
2016-03-12 11:26:00 | This study showed that GluA3 is uniformly distributed along the synapse, and seldom extends beyond its lateral border in hippocamoys. | 25524891 |
2013-11-16 10:07:00 | The results of this study support the local translation of GluA1-4 mRNAs in dendrites of hippocampal pyramidal cells and CA1 interneurons but not in granule cells of the dentate gyrus. | 23296627 |
2013-10-19 12:18:00 | A decrease in GluA1 and increases in GluA3 subunit and expression at the end of the third postnatal week provide a molecular explanation for the increase in AMPAR response duration and reduced efficacy of AMPAR modulators with increasing age. | 23884930 |
Type | IDs |
---|---|
Synonymous | GLUR3, GluA3, GluR-3, GluR-C, GluR-K3 |
Gene |
UniProtKB-ID:
GRIA3_RAT,
G3V8Y9_RAT,
G3V6Z5_RAT
UniprotKB:
P19492,
G3V8Y9,
G3V6Z5
UniParc:
UPI0000033423,
UPI0000251119,
UPI000019BA1D,
UPI000002AA92
EMBL:
X54656,
AABR07041368,
AABR07041369,
M85036,
M38062,
AABR07041370,
AABR07041371,
AABR07041373,
M36420,
AABR07041375,
CH473991,
AABR07041374,
AABR07041372
Ensembl:
ENSRNOG00000007682
KO:
rno:29628
|
Nucleutide sequences |
EMBL-CDS:
AAA63480.1,
CAA38466.1,
AAA41241.2,
AAA41245.1,
EDM10877.1,
EDM10878.1,
EDM10879.1
Gene_ORFName:
rCG_53210,
rCG_53210
Ensembl_TRS:
ENSRNOT00000029031,
ENSRNOT00000010367
|
Protein sequencees |
Ensembl_PRO:
ENSRNOP00000031170,
ENSRNOP00000010367
RefSeq:
XP_006257561.1,
XP_006257563.1,
XP_017457440.1,
NP_001106213.1,
XP_006257560.1,
XP_017457439.1,
NP_116785.2,
XP_006257558.1
|
Others |
UniRef100:
UniRef100_G3V8Y9,
UniRef100_G3V6Z5,
UniRef100_P19492
UniRef90:
UniRef90_P19492-2,
UniRef90_P19492
UniRef50:
UniRef50_P19492-2,
UniRef50_P19492
UniGene:
Rn.74049
|
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