| Type | Description |
|---|---|
| Definition | general transcription factor IIF subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-01 11:40:00 | An AR motif of the transactivation domain has been identified that contributes to transcriptional activity by recruiting the C-terminal domain of subunit 1 of the general transcription regulator TFIIF. | 29225078 |
| 2012-05-05 10:03:00 | These results suggest that Mediator structural shifts induced by activator binding help stably orient pol II prior to transcription initiation within the human mediator-RNA polymerase II-TFIIF assembly. | 22343046 |
| 2012-03-31 10:05:00 | Gdown1 competes with TFIIF for binding to the RPB1 and RPB5 subunits of Pol II, thereby inhibiting an essential function of TFIIF in preinitiation complex assembly. | 22244332 |
| 2011-12-17 11:40:00 | Data show that TFIIF has an important role in stabilizing TFIIB within the PIC and after transcription initiates. | 21896726 |
| 2010-01-21 00:00:00 | TFIIF and Rpb7 are involved in both early and late transcriptional stages | 17848138 |
| Type | IDs |
|---|---|
| Synonymous | BTF4, RAP74, TF2F1, TFIIF |
| Gene |
UniProtKB-ID:
T2FA_HUMAN
UniprotKB:
P35269
UniParc:
UPI000007323F
EMBL:
X64002,
BC000120,
BC013007,
BT007097,
AK315240,
CH471139,
X64037
Ensembl:
ENSG00000125651
KO:
hsa:2962
|
| Nucleutide sequences |
EMBL-CDS:
CAA45408.1,
AAP35761.1,
AAH00120.1,
AAH13007.1,
CAA45404.1,
BAG37667.1,
EAW69098.1
Ensembl_TRS:
ENST00000394456
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377969
RefSeq:
NP_002087.2,
XP_024307243.1
|
| Others |
UniRef100:
UniRef100_P35269
UniRef90:
UniRef90_P35269
UniRef50:
UniRef50_P35269
UniGene:
Hs.68257
CCDS:
CCDS12165.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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