| Type | Description |
|---|---|
| Definition | general transcription factor IIE subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-30 11:45:00 | functional analysis of Trichothiodystrophy causative TFIIEbeta mutation demonstrates that mutant TFIIEbeta strongly reduces the total amount of the entire TFIIE complex, with a remarkable temperature-sensitive transcription defect. | 28973399 |
| 2017-06-24 10:15:00 | The N-terminal half of TFIIEalpha forms an extended winged helix (WH) domain with an additional helix, followed by a zinc-finger domain. TFIIEbeta contains the WH2 domain, followed by two coiled-coil helices intertwining with TFIIEalpha. | 27639436 |
| 2016-09-03 10:16:00 | We underline role of TFIIE in transcription and its distinction from nucleotide excision repair. Trichothiodystrophy individuals with mutations in GTF2E2 highlight the importance of the direct interaction between TFIIH and TFIIE in transcription process. | 26996949 |
| 2015-05-30 11:07:00 | PC4 plays essential roles in the transition step from transcription initiation to elongation by binding to melted DNA in collaboration with TFIIEbeta. | 25308091 |
| 2010-01-21 00:00:00 | TFIIE is an alpha/beta heterodimer in solution; A model for the quaternary architecture of the complex is proposed that provides a structural framework to discuss the function of TFIIE in the context of RNA polymerase II transcription initiation. | 16547462 |
| Type | IDs |
|---|---|
| Synonymous | FE, TF2E2, TFIIE-B, TTD6 |
| Gene |
UniProtKB-ID:
T2EB_HUMAN
UniprotKB:
P29084
UniParc:
UPI00001367F4
EMBL:
BC030572,
X63469,
AF292057,
AF292056,
CH471080,
S67861,
AF292060,
AF292062,
AF292058,
AF292061,
AF292059
Ensembl:
ENSG00000197265
KO:
hsa:2961
|
| Nucleutide sequences |
EMBL-CDS:
AAB20414.1,
EAW63449.1,
CAA45069.1,
AAG39077.1,
EAW63446.1,
AAH30572.1
Ensembl_TRS:
ENST00000355904
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348168
RefSeq:
XP_016868853.1,
NP_002086.1,
XP_011542811.1,
XP_011542812.1,
XP_016868852.1,
XP_024302906.1,
NP_001335282.1
|
| Others |
UniRef100:
UniRef100_P29084
UniRef90:
UniRef90_P29084
UniRef50:
UniRef50_P29084
UniGene:
Hs.77100
CCDS:
CCDS6078.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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