| Type | Description |
|---|---|
| Definition | general transcription factor IIE subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:04:00 | the eWH domain of hTFIIEalpha can replace the first eWH (eWH1) domain of hRPC62 in ATPase and DNA unwinding assays. Our results identify intrinsic enzymatic activities in hRPC62 and hTFIIEalpha. | 31529052 |
| 2017-07-08 10:15:00 | The N-terminal highly acidic region of TFIIEalpha interacts with the pleckstrin homology domain of TFIIH and adopts an extended stringlike structure on the positive groove of the pleckstrin homology domain with two hydrophobic amino acids, Phe387 and Val390, inserting into two shallow hydrophobic pockets of the pleckstrin homology domain. | 27602723 |
| 2017-06-24 10:15:00 | The N-terminal half of TFIIEalpha forms an extended winged helix (WH) domain with an additional helix, followed by a zinc-finger domain. TFIIEbeta contains the WH2 domain, followed by two coiled-coil helices intertwining with TFIIEalpha. | 27639436 |
| 2015-10-03 10:17:00 | Association of the winged helix motif of the TFIIEalpha subunit of TFIIE with either the TFIIEbeta subunit or TFIIB distinguishes its functions in transcription. | 25492609 |
| 2010-01-21 00:00:00 | TFIIE is an alpha/beta heterodimer in solution. A model for the quaternary architecture of the complex is proposed that provides a structural framework to discuss the function of TFIIE in the context of RNA polymerase II transcription initiation. | 16547462 |
| Type | IDs |
|---|---|
| Synonymous | FE, TF2E1, TFIIE-A |
| Gene |
UniProtKB-ID:
T2EA_HUMAN
UniprotKB:
P29083
UniParc:
UPI000013DD5F
EMBL:
X63468,
S67859
Ensembl:
ENSG00000153767
KO:
hsa:2960
|
| Nucleutide sequences |
EMBL-CDS:
AAB20413.1,
CAA45068.1
Ensembl_TRS:
ENST00000283875
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000283875
RefSeq:
NP_005504.2
|
| Others |
UniRef100:
UniRef100_P29083
UniRef90:
UniRef90_P29083
UniRef50:
UniRef50_P29083
UniGene:
Hs.445272
CCDS:
CCDS3002.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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