| Type | Description |
|---|---|
| Definition | general transcription factor IIB |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7- and 9-nt RNAs. | 32417370 |
| 2018-12-01 11:38:00 | a hand-off model in which Ssu72 mediates a conformational transition in TFIIB, accounting for the role of Ssu72 in transcription reinitiation, gene looping, and promoter-terminator cross-talk. | 29158257 |
| 2016-07-30 10:48:00 | binding of specific DNA sequences changes the protein structure and dynamics, and TFIIB may exist in two conformational states | 26284261 |
| 2016-03-26 12:01:00 | The role of zinc at Cys3His1 binding site in the absence of TFIIB protein folding | 26016528 |
| 2015-10-24 10:41:00 | these results establish a new paradigm for TFIIB functionality in human gene expression, which when downregulated has potent anti-viral effects. | 24441171 |
| Type | IDs |
|---|---|
| Synonymous | TF2B, TFIIB |
| Gene |
UniProtKB-ID:
TF2B_HUMAN
UniprotKB:
Q00403
UniParc:
UPI0000136C21
EMBL:
AK289822,
AL445991,
BC020597,
S44184,
AB451296,
X59268,
M76766
Ensembl:
ENSG00000137947
KO:
hsa:2959
|
| Nucleutide sequences |
EMBL-CDS:
AAB23144.1,
CAA41958.1,
AAA61149.1,
BAF82511.1,
BAG70110.1,
AAH20597.1
Ensembl_TRS:
ENST00000370500
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359531
RefSeq:
NP_001505.1,
XP_011539601.1
|
| Others |
UniRef100:
UniRef100_Q00403
UniRef90:
UniRef90_Q00403
UniRef50:
UniRef50_Q00403
UniGene:
Hs.481852
CCDS:
CCDS715.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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