| Type | Description |
|---|---|
| Definition | POU class 3 homeobox 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:27:00 | results indicated that Brn4 promoted the neuronal differentiation of neural stem cells via inhibition of CtBP2 and is a potential tool for generating neurons in cell replacement therapy of neurodegenerative diseases and brain injury | 31518606 |
| 2012-06-09 11:23:00 | The co-transduction of Nurr1 and Brn4 genes induces cell differentiation of neural stem cells | 21663595 |
| 2010-07-26 11:28:00 | Brn-4 expression is required both for neuronal differentiation of NSCs and maturation of newborn neurons, and that there may be some regulatory factors in deafferented hippocampus that can regulate Brn-4 expression in neuronal progenitors. | 20105446 |
| 2010-01-21 00:00:00 | study showed after fimbria-fornix lesion, Brn-4 in deafferented hippocampus was upregulated & might play a role in inducing local progenitors to differentiate into neurons, which may compensate for loss of cholinergic afferent fibers or other dysfunctions | 18831054 |
| Type | IDs |
|---|---|
| Synonymous | RHS2 |
| Gene |
UniProtKB-ID:
PO3F4_RAT
UniprotKB:
P62516
UniParc:
UPI0000025229
EMBL:
M84645,
Z11834
Ensembl:
ENSRNOG00000002784
KO:
rno:29589
|
| Nucleutide sequences |
EMBL-CDS:
CAA77855.1,
AAA42042.1
Ensembl_TRS:
ENSRNOT00000003724
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000003724
RefSeq:
NP_058948.1
|
| Others |
UniRef100:
UniRef100_P62515
UniRef90:
UniRef90_P49335
UniRef50:
UniRef50_P49335
UniGene:
Rn.33030
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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