| Type | Description |
|---|---|
| Definition | general transcription factor IIA subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 10:32:00 | De novo produced TFIIA is rapidly confined to the cytoplasm via an evolutionary conserved nuclear export signal (NES, amino acids 21VINDVRDIFL30), interacting with the nuclear export receptor Exportin-1/chromosomal region maintenance 1 (Crm1). | 28992066 |
| 2019-07-20 11:52:00 | Proteolytic processing of TFIIA by Taspase1 was found to mask evolutionary conserved nuclear export signal, thereby promoting nuclear localization and transcriptional activation of TFIIA target genes, such as CDKN2A. | 29097782 |
| 2017-11-25 15:08:00 | In a cohort of youth at risk for bipolar disorder, pathway analysis showed an enrichment of the glucocorticoid receptor (GR) pathway with the genes MED1, GTF2A1 and TAF15, which might underlie the previously reported role of stress response in the risk for bipolar disorder in vulnerable populations. | 28291257 |
| 2017-08-05 10:32:00 | Data suggest that many TATA-box-containing promoters contain a TFIIA recognition element (IIARE) that activates transcription by increasing the recruitment of RNA polymerase II, TFIIA (TF2A1/TF2A2 subunits), TAF4, and P300. (TAF4 = TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1; P300 = E1A binding protein p300) | 28539359 |
| 2017-02-18 10:06:00 | The interaction of TBP-like protein with TFIIA is essential to suppress proteasome-dependent turnover of TBP-like protein | 27696626 |
| Type | IDs |
|---|---|
| Synonymous | TF2A1, TFIIA, TFIIA-42, TFIIAL |
| Gene |
UniProtKB-ID:
TF2AA_HUMAN
UniprotKB:
P52655
UniParc:
UPI000016AFB5,
UPI00001367C0
EMBL:
D14886,
X77225,
AC010582,
D14887,
X75383,
BC107155,
BC107156
Ensembl:
ENSG00000165417
KO:
hsa:2957
|
| Nucleutide sequences |
EMBL-CDS:
AAF26776.1,
AAI07157.1,
BAA03603.1,
CAA53151.1,
AAI07156.1,
BAA03604.1,
CAA54442.1,
CAA53152.1
Ensembl_TRS:
ENST00000434192,
ENST00000553612
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000452454,
ENSP00000409492
RefSeq:
NP_056943.1,
NP_001265869.1,
NP_963889.1
|
| Others |
UniRef100:
UniRef100_P52655
UniRef90:
UniRef90_P52655
UniRef50:
UniRef50_P52655
UniGene:
Hs.592334
CCDS:
CCDS9874.1,
CCDS9873.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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