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29539 Aldh2

29539

Aldh2

aldehyde dehydrogenase 2 family (mitochondrial)

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition aldehyde dehydrogenase 2 family (mitochondrial)

研究结论

Date Results Publications
2020-05-23 11:03:00 animals jointly receiving nitroglycerin (GTN) and disulfiram (DSF) developed tolerance to GTN, and in animals that in addition to GTN and DSF also received lipoic acid (LA) such tolerance did not develop, is - in our opinion - a sufficient premise to conclude that the nitrate tolerance certainly is not caused by a decrease in the activity of any of the ALDH isoenzymes present in the rat liver, including ALDH2. 31883320
2019-08-24 11:06:00 Mitochondrial ALDH2 inhibits the proliferation of neonatal rat cardiac fibroblasts induced by high glucose, and the effect is possibly mediated by the up-regulation of autophagy-related proteins Beclin-1 and LC3B. 31140414
2019-04-20 11:11:00 increasing ALDH2 activity can improve brain edema, infarct volumes 29767275
2019-04-06 10:50:00 Activation of aldehyde dehydrogenase 2 by low concentration of ethanol can reduce myocardial injury and fibrosis caused by diabetes, and its mechanism may be related to the changes of the two-por potassium channel TASK-1 30837397
2019-03-02 12:02:00 Results suggest that activation of ALDH2 by Alda-1 improves depressive-like behavior in rats after myocardial infarction by increasing VEGF expression in the hippocampus of rats. 29574217

名称对应

Type IDs
Gene
UniProtKB-ID: ALDH2_RAT, F1LN88_RAT
UniprotKB: P11884, F1LN88
UniParc: UPI00015503B9, UPI0000129296
EMBL: AF529165, X14977, M19030, CH473973, AY566469, AABR07036374, AY034137, AY566468, AABR07036373, AY566467, BC062081
Ensembl: ENSRNOG00000001344
KO: rno:29539
Nucleutide sequences
EMBL-CDS: AAK57732.1, CAA33101.1, AAS75815.1, AAH62081.1, AAA40719.1, AAM94394.2, AAS75814.1, AAS75813.1, EDM13725.1, EDM13724.1, EDM13726.1
Gene_ORFName: rCG_21519
Ensembl_TRS: ENSRNOT00000001816
Protein sequencees
Ensembl_PRO: ENSRNOP00000001816
RefSeq: NP_115792.1, XP_006249447.1
Others
UniRef100: UniRef100_F1LN88, UniRef100_P11884
UniRef90: UniRef90_P11884
UniRef50: UniRef50_P11884
UniGene: Rn.101781

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