| Type | Description |
|---|---|
| Definition | serum/glucocorticoid regulated kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:34:00 | Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1-NKCC1 Pathway. | 32645929 |
| 2020-12-12 13:29:00 | Upregulation of serum and glucocorticoid-regulated kinase 1 exacerbates brain injury and neurological deficits after cardiac arrest. | 32946263 |
| 2019-11-02 10:46:00 | knocking down SGK1 expression significantly downregulated phosphorylated-FOXO3a and HIF-1alpha and suppressed LC3II and Beclin-1 levels. | 29497029 |
| 2018-12-22 10:18:00 | HIF-1a could induce miR-145 upregulation in hypoxic H9c2 and HL-1 cells. MiR-145 protected H9c2 cells against hypoxic damage. SGK1 upregulation and activated PI3K/AKT may have participated in the protective effects of miR-145 on cardiomyocytes. | 28980287 |
| 2018-02-10 11:06:00 | Sequential and tandem ChIP analyses showed that, after forced swim (FS) stress , MRs and GRs bind concomitantly to the same GRE sites within Fkbp5 and Per1 but not Sgk1 Thus, after stress, MRs and GRs seem to bind to GREs as homo- and/or heterodimers in a gene-dependent manner. MR binding to GREs at baseline seems to be restricted, whereas after stress, GR binding may facilitate cobinding of MR | 27655894 |
| Type | IDs |
|---|---|
| Synonymous | Sgk |
| Gene |
UniProtKB-ID:
A0A0G2JVM7_RAT,
D4A128_RAT,
Q68G05_RAT,
F1LXA3_RAT
UniprotKB:
A0A0G2JVM7,
D4A128,
Q68G05,
F1LXA3
UniParc:
UPI0003D0DF26,
UPI0000DC1DC8,
UPI000017A3E8,
UPI0001DD380C
EMBL:
BC078843,
AABR07000720,
AABR07000719,
CH474002
Ensembl:
ENSRNOG00000011815
KO:
rno:29517
|
| Nucleutide sequences |
EMBL-CDS:
AAH78843.1,
EDL87730.1
Gene_ORFName:
rCG_42017
Ensembl_TRS:
ENSRNOT00000083452,
ENSRNOT00000061157,
ENSRNOT00000016121,
ENSRNOT00000040736
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000069545,
ENSRNOP00000057871,
ENSRNOP00000016121,
ENSRNOP00000046277
RefSeq:
NP_062105.2,
NP_001180497.1,
NP_001180498.1,
XP_006227785.1
|
| Others |
UniRef100:
UniRef100_Q68G05,
UniRef100_D4A128,
UniRef100_F1LXA3,
UniRef100_A0A0G2JVM7
UniRef90:
UniRef90_Q9WVC6,
UniRef90_Q9WVC6-2,
UniRef90_A0A4X1VDA7,
UniRef90_G3W1X6
UniRef50:
UniRef50_O00141,
UniRef50_Q6GPN6,
UniRef50_Q06226,
UniRef50_Q9WVC6
UniGene:
Rn.4636
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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