| Type | Description |
|---|---|
| Definition | relaxin family peptide receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 11:22:00 | This study demonstrates the involvement of ADAM10 and PI3K/Akt signaling in mediating RLX-induced Notch-1 activation. | 29180109 |
| 2018-06-09 10:40:00 | Relaxin-1 mRNA in the hearts of diabetic rats was significantly increased and that relaxin-3 mRNA expression at different time points was decreased. In addition, significant down-regulation of the mRNA expression of RXFP1 and RXFP3 was observed at 4 weeks after Streptozocin. | 28776188 |
| 2015-12-26 11:55:00 | Results suggest that changes in relaxin family peptides (RXFP3, RXFP1) may contribute to the significant sex differences observed in the hippocampus and amygdala as a function of aging | 25313002 |
| 2015-02-14 11:40:00 | Data indicate that knee passive range of motion (ROM), relaxin receptor isoforms Rxfp1 and Rxfp2 expression were significantly reduced following treatment with testosterone, and androgen antagonist flutamide antagonized the testosterone effect. | 24642882 |
| 2014-09-20 11:51:00 | RXFP1 & RXFP2 up-regulation by progesterone and estrogen could provide the basis for the reported increase in knee laxity while down-regulation of these receptor isoforms by testosterone could explain low incidence of non-contact knee injury in male. | 24465164 |
| Type | IDs |
|---|---|
| Synonymous | Lgr7 |
| Gene |
UniProtKB-ID:
RXFP1_RAT
UniprotKB:
Q6R6I6
UniParc:
UPI0000236DE7
EMBL:
AY509976
KO:
rno:295144
|
| Nucleutide sequences |
EMBL-CDS:
AAR97516.1
|
| Protein sequencees |
RefSeq:
XP_008759310.1,
XP_006232572.1,
NP_958820.1,
XP_008759309.1,
XP_008759307.1,
XP_017446248.1,
XP_008759308.1,
XP_006232570.1,
XP_017446249.1
|
| Others |
UniRef100:
UniRef100_Q6R6I6
UniRef90:
UniRef90_Q6R6I7
UniRef50:
UniRef50_Q8WXD0
UniGene:
Rn.109230
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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