Type | Description |
---|---|
Definition | membrane associated ring-CH-type finger 6 |
Date | Results | Publications |
---|---|---|
2017-01-28 11:09:00 | High iodine intake had no discernible effects on USP20. Temporary increases in USP33 and USP19 mRNA levels were observed. The enzymes related to D2 ubiquitination change with prolonged high iodine intake. Increased D2 ubiquitination suppresses the activity of D2, causing a decrease in negative feedback of the hypothalamic-pituitary-thyroid axis. | 27156111 |
2010-01-21 00:00:00 | TEB4 interacts with and mediates loss of type 2 iodothyronine deiodinase (D2)activity, indicating that D2 ubiquitination and degradation can be tissue specific, depending on WSB-1 and TEB4 expression levels. | 19651899 |
Type | IDs |
---|---|
Synonymous | RGD1310927, RGD1565757 |
Gene |
UniProtKB-ID:
F1M1F1_RAT
UniprotKB:
F1M1F1
UniParc:
UPI0001CF3D72
EMBL:
AABR07009034
Ensembl:
ENSRNOG00000011066
KO:
rno:294862
|
Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000028561
|
Protein sequencees |
Ensembl_PRO:
ENSRNOP00000028561
RefSeq:
XP_008759048.1,
NP_001292203.1
|
Others |
UniRef100:
UniRef100_F1M1F1
UniRef90:
UniRef90_Q6ZQ89
UniRef50:
UniRef50_O60337
UniGene:
Rn.2039
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
27156111 |
Biol Trace Elem Res Xiaowen Zhang , Yaqiu Jiang , Wenqing Han , Aihua Liu , Xiaochen Xie , Cheng Han , Chenling Fan , Hong Wang , Hongmei Zhang , Shuangning Ding , Zhongyan Shan , Weiping Teng |
2016-12-01 | - |
25088257 |
Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6. Exp Cell Res Nobuhiro Nakamura , Kumi Harada , Masako Kato , Shigehisa Hirose |
2014-10-15 | - |
24449766 |
Mol. Cell. Biol. Noam Zelcer , Laura J Sharpe , Anke Loregger , Ika Kristiana , Emma C L Cook , Lisa Phan , Julian Stevenson , Andrew J Brown |
2014-04-01 |
MARCH6,
HMGCR,
SQLE
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
19946888 |
Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins |
2010-01-01 |
MED6,
PDCD6IP,
MED16,
PIGK,
DNAJB6,
FARSB,
DNM1L,
ABCF2,
HUWE1,
ARPC3,
ACTR3,
ACTR2,
RAD50,
PREB,
ACTR1B,
LRPPRC,
TRAP1,
BCAP31,
PLXNC1,
LPCAT3,
TNK2,
PSME3,
MPHOSPH9,
FLOT1,
DDX39A,
AK6,
ADAM10,
PLIN3,
CALCOCO2,
CDK9,
ABCC4,
ZMPSTE24,
AKAP8,
BET1,
MARCH6,
KATNB1,
ADAR,
EMC8,
BTN3A3,
ATP8A1,
NDC80,
CDIPT,
PGRMC2,
TUBGCP3,
ECI2,
COG5,
SLC25A17,
LRRC41,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
HYOU1,
IPO7,
NOP56,
ARL6IP5,
HTATIP2,
AGPAT1,
ARFGEF2,
RABAC1,
SLU7,
PRPF8,
PAICS,
CENPE,
PMVK,
KHDRBS1,
CELF1,
GNA13,
CFL1,
MGEA5,
YME1L1,
STAG2,
CTSC,
GIPC1,
HBS1L,
TUBGCP2,
PGRMC1,
MAN1A2,
PNPLA6,
MAGED2,
ADCY3,
EHD1,
TOMM34,
ERP29,
YWHAQ,
ASCC3,
GCN1,
IMMT,
ILVBL,
SLC27A4,
SLC27A3,
KIF2C,
GLIPR1,
CPSF6,
DDX52,
WWP2,
CNTRL,
CHD4,
KRR1
|
19651899 |
The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Mol Cell Biol Ann Marie Zavacki , Rafael Arrojo E Drigo , Beatriz C G Freitas , Mirra Chung , John W Harney , Péter Egri , Gábor Wittmann , Csaba Fekete , Balázs Gereben , Antonio C Bianco |
2009-10-01 | - |
16373356 |
J Biol Chem Stefan G Kreft , Lin Wang , Mark Hochstrasser |
2006-02-24 | - |
15673284 |
TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum. Biochem. J. Gerco Hassink , Marjolein Kikkert , Sjaak van Voorden , Shiow-Ju Lee , Robbert Spaapen , Theo van Laar , Catherine S Coleman , Eric Bartee , Klaus Früh , Vincent Chau , Emmanuel Wiertz |
2005-06-01 |
MARCH6,
UBC,
UBE2G1
|
15632090 |
Gene and alternative splicing annotation with AIR. Genome Res. Liliana Florea , Valentina Di Francesco , Jason Miller , Russell Turner , Alison Yao , Michael Harris , Brian Walenz , Clark Mobarry , Gennady V Merkulov , Rosane Charlab , Ian Dew , Zuoming Deng , Sorin Istrail , Peter Li , Granger Sutton |
2005-01-01 |
Zfp867,
LOC100125362,
LOC100125364,
LOC100125367,
Ces1f,
Adat3,
Nudcd3,
LOC100125384,
Mroh1,
LOC100125598,
Rab1b,
Mfsd14a,
LOC100134871,
Usp43,
Phykpl,
Nrn1l,
Hexdc,
LOC100233176,
Zfp949,
LOC100233206,
Spns2,
Tas1r2,
LOC100271872,
LOC100302465,
Tas2r136,
Tas2r116,
Tas2r129,
Nemf,
Zfp831,
Znhit1,
E2f4,
Galnt15,
Rnh1,
Hsh2d,
Zranb1,
LOC100360645,
Fosb,
LOC100360933,
Mycbp,
Dgkq,
Prr9,
Tbcd,
Armc3,
Psmg3,
Rpl37a,
Rad9a,
Ano2,
Hoxb2,
Tram2,
Mta3,
Ppp1r2-ps1,
Ttc30a,
Gpr82,
Epc1,
Ddx55,
Txndc5,
Henmt1,
Cystm1,
Rab37,
LOC100365112,
Med7,
LOC100911593,
Clec3b,
Rps27a,
Nupr1,
Enho,
Tigd2,
Ak6,
LOC102546764,
Bivm,
Vcpkmt,
Samd11,
Xrcc3,
Tctex1d4,
Eml3,
LOC102553549,
Trim30c,
Rcor1,
Wdr90,
Hoxa2,
Hoxa3,
Hoxa1,
Peg3,
LOC103691425,
Ubl4b,
LOC103692678,
Oxld1,
LOC103693512,
Tjp2,
Crnkl1-ps1,
Nrxn2,
Slc17a7,
Oxr1,
Il13ra2,
Ces2c,
Ahnak,
Ubb,
Acp1,
Ak2
|
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
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