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29483 Slc1a3

29483

Slc1a3

solute carrier family 1 member 3

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition solute carrier family 1 member 3

研究结论

Date Results Publications
2017-11-25 13:44:00 This study showed an increased expression of glial (GLAST and GLT-1) after paraoxon exposure. 27769869
2017-07-15 10:19:00 EAAT1 is regulated by CaMKII signaling and is a critical driver of constitutive glutamate uptake by EAAT1. 27889915
2017-07-01 10:27:00 Astrocyte expression of GLAST/GFAP was reduced via signaling pathway after exposure to sevoflurane. 27003918
2017-06-24 11:34:00 Spinal glial glutamate transporters GLAST and GLT-1 have protective function by reducing and preventing selectively non-evoked pain behavior after incision. This is a result of increased GLAST expression regulated by the MAPK p38 after incision 26920805
2017-03-04 12:30:00 Results suggest that, via astrocytes, IL-17A could promote glutamate excitotoxicity in multiple terms: by decreasing the astrocyte ability to uptake extracellular glutamate, due to a reduced gene expression of glutamate transporters (GLAST and GLT-1); by decreasing intracellular glutamate conversion into non-toxic glutamine; by potentiating glutamate exocytosis in a Ca2+ dependent manner 28104249

名称对应

Type IDs
Synonymous EAAT1, GLAST, GLAST-1, GluT-1
Gene
UniProtKB-ID: EAA1_RAT, G3V846_RAT, A0A0G2K611_RAT, A0A0G2JSU1_RAT, A0A0G2KAS7_RAT
UniprotKB: P24942, G3V846, A0A0G2K611, A0A0G2JSU1, A0A0G2KAS7
UniParc: UPI000016794F, UPI0000129B10, UPI00001706EC, UPI000002A89A, UPI0003EC61F7, UPI0003EBD0BD
EMBL: AF265360, S75687, X63744, AABR07008424, S59158, CH474048, AABR07008423
Ensembl: ENSRNOG00000016163
KO: rno:29483
Nucleutide sequences
EMBL-CDS: AAB32664.1, AAF73069.1, AAB26422.1, CAA45276.1, EDL75679.1, EDL75680.1
Gene_ORFName: rCG_50959, rCG_50959
Ensembl_TRS: ENSRNOT00000022319, ENSRNOT00000077790, ENSRNOT00000035821, ENSRNOT00000085599
Protein sequencees
Ensembl_PRO: ENSRNOP00000022319, ENSRNOP00000073634, ENSRNOP00000036554, ENSRNOP00000075509
RefSeq: XP_017446210.1, NP_001276872.1, NP_001276870.1, NP_062098.1, NP_001276871.1
Others
UniRef100: UniRef100_A0A0G2JSU1, UniRef100_A0A0G2KAS7, UniRef100_A0A0G2K611, UniRef100_P24942, UniRef100_G3V846
UniRef90: UniRef90_A0A0G2K611, UniRef90_P43003
UniRef50: UniRef50_A0A2I2YRP4, UniRef50_P43003
UniGene: Rn.34134

全选

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研究热度

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