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29477 Mapt

29477

Mapt

microtubule-associated protein tau

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition microtubule-associated protein tau

研究结论

Date Results Publications
2021-02-06 13:58:00 Truncation of Tau selectively facilitates its pathological activities. 32737201
2021-01-16 15:57:00 A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-beta toxicity. 31698056
2020-10-24 13:57:00 Inhibition of PDE5 attenuates streptozotocin-induced neuroinflammation and tau hyperphosphorylation in a streptozotocin-treated rat model. 31344367
2020-03-07 11:08:00 Described is a new role for N-terminal human tau region comprising residues 16 to 26. That region is present in human Tau but not in mouse or rat Tau. Tau N-terminal end is a binding site for creatine Kinase B. 31189515
2019-11-30 11:30:00 glycemic variability might induce diabetic central neuropathy through the hyperphosphorylation of Tau in the hippocampus by inhibiting the Akt/GSK3beta pathway and that it may cause diabetic neuropathy through oxidative stress and inflammatory responses by activating the NF-kappaB pathway. 30660367

名称对应

Type IDs
Synonymous Mtapt, RNPTAU, Tau, pTau
Gene
UniProtKB-ID: D3ZKD9_RAT, D4A1Q2_RAT, F1LST4_RAT, A0JN25_RAT
UniprotKB: D3ZKD9, D4A1Q2, F1LST4, A0JN25
UniParc: UPI000019B8B5, UPI0000500F0F, UPI0000E67410, UPI0000500F11
EMBL: BC126095, AABR07030527, CH473948, AABR07030528
Ensembl: ENSRNOG00000005133
KO: rno:29477
Nucleutide sequences
EMBL-CDS: EDM06301.1, EDM06299.1, EDM06303.1, AAI26096.1
Gene_ORFName: rCG_32645, rCG_32645, rCG_32645
Ensembl_TRS: ENSRNOT00000006947, ENSRNOT00000050070, ENSRNOT00000042984, ENSRNOT00000045127
Protein sequencees
Ensembl_PRO: ENSRNOP00000006947, ENSRNOP00000040951, ENSRNOP00000042392, ENSRNOP00000051451
RefSeq: NP_058908.2, XP_017452664.1, XP_008766500.1, XP_008766490.1, XP_008766492.1, XP_008766493.1, XP_008766495.1, XP_008766494.1, XP_008766503.1, XP_008766502.1, XP_008766499.1, XP_008766491.1, XP_008766501.1, XP_008766504.1
Others
UniRef100: UniRef100_D3ZKD9, UniRef100_F1LST4, UniRef100_D4A1Q2, UniRef100_A0JN25
UniRef90: UniRef90_P10637, UniRef90_P19332-7, UniRef90_P19332-5
UniRef50: UniRef50_P10637, UniRef50_P10636-2
UniGene: Rn.2455

全选

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