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2946 GSTM2

2946

GSTM2

glutathione S-transferase mu 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutathione S-transferase mu 2

研究结论

Date Results Publications
2018-03-31 10:49:00 the methylation status of CpG sites in GFRA1 and GSTM2 may have a role and could be used as potential biomarkers for the screening of rectal cancer 27566576
2015-05-16 12:55:00 The absence of GSTM1 and GSTT1 genes increases the risk of lung cancer because of radon exposure. 24852519
2014-06-28 12:13:00 the absence of GSTM1 activity can be compensated for by the overexpression of GSTM2. 24048194
2014-06-28 10:31:00 demonstrated that the GSTM1 and GSTT1 null genotype may be associated with an increased risk of Hepatocellular carcinoma (HCC) and that individuals having the combination of both defective GST genotypes may be more susceptible to developing HCC 24399650
2013-12-14 10:34:00 High expression of GSTM1 and GSTM4, along with increased endogenous reduced glutathione levels, help to maintain a more reduced state of cytochrome c which decreases apoptosis thus contributing to methotrexate resistance in human MCF7 breast cancer cells. 23675469

名称对应

Type IDs
Synonymous GST4, GSTM, GSTM2-2, GTHMUS
Gene
UniProtKB-ID: GSTM2_HUMAN, Q0D2I8_HUMAN, A0A384P5E9_HUMAN
UniprotKB: P28161, Q0D2I8, A0A384P5E9
UniParc: UPI000186C9D2, UPI0000DF09E0, UPI000013CAC9
EMBL: AC000032, BC105038, BT019947, AK299482, M63509, BC110380, CH471122, AC000031, BC105066, GQ891333
Ensembl: ENSG00000213366
KO: hsa:2946
Nucleutide sequences
EMBL-CDS: AAI05067.1, BAG61446.1, AAV38750.1, AAA60963.1, AAI05039.1, AAI10381.1, ADO22195.1, EAW56406.1
Gene_ORFName: hCG_2039123
Ensembl_TRS: ENST00000460717, ENST00000442650, ENST00000241337
Protein sequencees
Ensembl_PRO: ENSP00000416883, ENSP00000241337, ENSP00000435910
RefSeq: NP_000839.1, NP_001135840.1
Others
UniRef100: UniRef100_Q0D2I8, UniRef100_P28161
UniRef90: UniRef90_P28161
UniRef50: UniRef50_P09488-2
UniGene: Hs.279837
CCDS: CCDS808.1, CCDS44192.1

全选

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