| Type | Description |
|---|---|
| Definition | mitochondrial calcium uniporter |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 11:51:00 | This study, identified the role of the Pyk2/MCU pathway in the regulation of mitochondrial Ca2+ uptake and apoptotic signaling after ischemic stroke. | 28916471 |
| 2017-10-07 13:02:00 | It has been shown that the propagation of the TRPV1-induced cytosolic calcium and sodium fluxes into mitochondria is dependent on coordinated activity of NCLX and MCU. | 27627464 |
| 2017-09-30 10:21:00 | MCU and EMRE proteins were mainly targeting to the IMM-outer mitochondrial membrane. | 27637331 |
| 2016-08-20 10:38:00 | Results suggest that both MCU and MICU1 are involved in mitochondrial Ca(2+) uptake in mast cells, while MCU plays a role in mast cell degranulation. | 26350567 |
| 2015-10-31 11:29:00 | These findings strongly suggest that MCU could be the major route for iron uptake into cardiac mitochondria | 24034353 |
| Type | IDs |
|---|---|
| Synonymous | Ccdc109a |
| Gene |
UniProtKB-ID:
A0A0G2K059_RAT,
M0RDI5_RAT
UniprotKB:
A0A0G2K059,
M0RDI5
UniParc:
UPI0000DA4453,
UPI0003D0838C
EMBL:
CH474016,
AABR07044975,
AABR07044974
Ensembl:
ENSRNOG00000045920
KO:
rno:294560
|
| Nucleutide sequences |
EMBL-CDS:
EDL93071.1
Gene_ORFName:
rCG_22037
Ensembl_TRS:
ENSRNOT00000090771,
ENSRNOT00000071477
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000071314,
ENSRNOP00000067686
RefSeq:
XP_017457119.1,
XP_017457121.1,
XP_017457120.1,
NP_001099868.1,
XP_017457118.1
|
| Others |
UniRef100:
UniRef100_M0RDI5,
UniRef100_A0A0G2K059
UniRef90:
UniRef90_A0A0G2K059,
UniRef90_Q3UMR5
UniRef50:
UniRef50_Q8NE86
UniGene:
Rn.44172
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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