| Type | Description |
|---|---|
| Definition | RAB7A, member RAS oncogene family |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 11:39:00 | the functions of RAB18 and RAB7 in lysosomal and autophagic activities may constitute an overlapping mechanism underlying Warburg micro syndrome and Charcot-Marie-Tooth Neuropathy Type 2B pathogenesis in the nervous system. | 30721447 |
| 2019-09-21 12:13:00 | demonstrated that autophagy regulates Matrix metalloproteinase-2 activity in a Rab7-dependent manner | 29932881 |
| 2018-04-07 11:51:00 | autophagosome maturation was enhanced by the activation of Rab7 via UVRAG-Vps16 interaction, which further demonstrated the potential neuroprotective role of Rab7 in Hypoxic preconditioning against transient global cerebral ischemia-induced neuronal injury in adult rats. | 28726776 |
| 2017-12-30 10:39:00 | increased endolysosomal iron causes cell death associated with increased cytosolic oxidative stress as well as autophagic impairments, and these effects are subject to modulation by endolysosomal ion channel activity in a RAB7A-dependent manner | 27383256 |
| 2016-09-03 10:52:00 | Rab7 regulates CDH1 endocytosis, circular dorsal ruffles genesis, and thyroglobulin pinocytosis in a thyroid cell line. | 26599499 |
| Type | IDs |
|---|---|
| Synonymous | Rab7 |
| Gene |
UniProtKB-ID:
RAB7A_RAT
UniprotKB:
P09527
UniParc:
UPI0000133051
EMBL:
X12535,
AB158427,
BC072470,
AF286535,
AB158428
Ensembl:
ENSRNOG00000012247
KO:
rno:29448
|
| Nucleutide sequences |
EMBL-CDS:
CAA31053.1,
BAE17000.1,
AAG00543.1,
AAH72470.1,
BAE16999.1
Ensembl_TRS:
ENSRNOT00000016432
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016432
RefSeq:
XP_006236911.1,
NP_076440.1
|
| Others |
UniRef100:
UniRef100_P09527
UniRef90:
UniRef90_P51149
UniRef50:
UniRef50_P51149
UniGene:
Rn.1425
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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