| Type | Description |
|---|---|
| Definition | cytochrome p450 oxidoreductase |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 11:17:00 | The structure of four-electron-reduced, NADP(+)-bound wild type CYPOR shows the plane of the nicotinamide ring positioned perpendicular to the FAD isoalloxazine with its carboxamide group forming H-bonds with N1 of the flavin ring and the Thr535 hydroxyl group. | 29308883 |
| 2017-12-16 10:53:00 | the N-terminus of CYP2J2 is very important to form a productive CYP-CPR complex to facilitate electron transfer. | 25450017 |
| 2017-08-26 11:07:00 | Data suggest CYP17A1, with electron donor NADPH-P450 reductase, is inherently distributive enzyme but that some processivity is present; some 17alpha-hydroxy pregnenolone formed does not dissociate from CYP17A1 before conversion to dehydroepiandrosterone; CYB5A does not enhance reaction by decreasing k(off) of ligands of CYP17A1. (CYP17A1 = cytochrome P450, family 17, subfamily A, polypeptide 1; CYB5A = cytochrome b5) | 28684414 |
| 2016-12-17 10:11:00 | The DeltaGly-143 protein had moderately decreased activity with cytochrome P450 and cytochrome c. It formed a flexible loop, which transiently interacts with the flavin N5, resulting in the generation of both an unstable neutral blue semiquinone and hydroquinone. | 27189945 |
| 2015-05-09 12:19:00 | The findings provide insights into the function of CPR and CPR-cyt c interaction on a structural basis. | 25512382 |
| Type | IDs |
|---|---|
| Synonymous | CYPOR |
| Gene |
UniProtKB-ID:
NCPR_RAT
UniprotKB:
P00388
UniParc:
UPI0000156D0F
EMBL:
M10068,
M58935,
M58933,
M58936,
M58932,
M58934,
M58937,
M12516
Ensembl:
ENSRNOG00000001442
KO:
rno:29441
|
| Nucleutide sequences |
EMBL-CDS:
AAA41067.1,
AAA41064.1,
AAA41683.1
Ensembl_TRS:
ENSRNOT00000001961
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001961
RefSeq:
NP_113764.1
|
| Others |
UniRef100:
UniRef100_P00388
UniRef90:
UniRef90_P00388
UniRef50:
UniRef50_P00388
UniGene:
Rn.11359
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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