| Type | Description |
|---|---|
| Definition | p21 (RAC1) activated kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:27:00 | Up-regulation of P21-activated kinase 1 in osteoarthritis chondrocytes is responsible for osteoarthritic cartilage destruction. | 31868209 |
| 2020-06-27 11:52:00 | MiRNA-221 regulates proliferation, apoptosis and insulin secretion in islet beta cells through targeting PAK1, thus protecting gestational diabetes mellitus -induced islet dysfunction in a rat model | 31587871 |
| 2018-11-03 11:38:00 | These results expand the model of insulin-stimulated glucose uptake in skeletal muscle cells by implicating p41ARC as a new component of the insulin-signaling cascade and connecting PAK1 signaling to N-WASP-cortactin-mediated actin polymerization and GLUT4 vesicle translocation. | 28972183 |
| 2017-11-11 11:36:00 | the oxidative stress-induced down-regulation of PAK1 activity could be involved in the loss of mesencephalic dopaminergic neurons. | 27121078 |
| 2017-06-24 11:35:00 | PAK-mediated phosphorylation of PKD1 at Ser203 triggers its membrane dissociation and subsequent entry into the nucleus, thereby regulating the phosphorylation of PKD1 nuclear targets, including class IIa histone deacetylases. | 28408623 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PAK1_RAT
UniprotKB:
P35465
UniParc:
UPI000013121D
EMBL:
U23443,
U49953
Ensembl:
ENSRNOG00000029784
KO:
rno:29431
|
| Nucleutide sequences |
EMBL-CDS:
AAB95646.1,
AAB61533.1
Ensembl_TRS:
ENSRNOT00000049321,
ENSRNOT00000091952
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073036,
ENSRNOP00000045832
RefSeq:
XP_006229814.1,
NP_058894.1,
XP_006229816.1,
XP_006229815.1
|
| Others |
UniRef100:
UniRef100_P35465
UniRef90:
UniRef90_P35465
UniRef50:
UniRef50_Q13153
UniGene:
Rn.9149
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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