| Type | Description |
|---|---|
| Definition | menin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:26:00 | Wild-type menin is rapidly degraded via the ubiquitin-proteasome pathway in a rat insulinoma cell line. | 31652443 |
| 2020-02-15 13:04:00 | results have uncovered a previously unappreciated physiological link in which GLP-1 signaling suppresses menin function through phosphorylation-triggered and actin/myosin cytoskeletal protein-mediated derepression of gene transcription. | 30792230 |
| 2015-04-11 13:51:00 | CDK4 is a critical downstream target of MEN1-dependent tumor suppression and is required for tumorigenic proliferation in the pituitary and pancreatic islet, whereas CDK2 is dispensable for tumorigenesis in these neuroendocrine cell types. | 24531709 |
| 2015-03-21 13:17:00 | These findings indicate that miR-29b represses translation of Men1 mRNA, in turn affecting intestinal epithelial homoeostasis by altering IEC apoptosis. | 25317587 |
| 2012-03-31 10:05:00 | This study suggests that menin might serve as an important intracellular target of glucose to mediate the mitogenic effect that glucose exerts in pancreatic beta-cells. | 22166975 |
| Type | IDs |
|---|---|
| Synonymous | menin |
| Gene |
UniProtKB-ID:
MEN1_RAT
UniprotKB:
Q9WVR8
UniParc:
UPI00000E8A74,
UPI000021E51F
EMBL:
CH473953,
AF130370,
AF130369,
AB023400
Ensembl:
ENSRNOG00000021054
KO:
rno:29417
|
| Nucleutide sequences |
EMBL-CDS:
EDM12595.1,
AAF01353.1,
EDM12593.1,
BAA82134.1,
EDM12594.1,
AAF01354.1
Ensembl_TRS:
ENSRNOT00000028592
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000028592
RefSeq:
NP_062081.1,
XP_006230834.1,
XP_006230832.1,
XP_006230833.1,
XP_006230831.1
|
| Others |
UniRef100:
UniRef100_Q9WVR8
UniRef90:
UniRef90_O00255
UniRef50:
UniRef50_O00255
UniGene:
Rn.6775
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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