| Type | Description |
|---|---|
| Definition | sphingosine-1-phosphate receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:56:00 | Sphingosine-1-phosphate receptor 2 modulates pain sensitivity by suppressing the pathway in a rat model of neuropathy. | 31603252 |
| 2019-10-12 12:39:00 | Testosterone regulates the expression and functional activity of sphingosine-1-phosphate receptors in the rat corpus cavernosum. | 29266713 |
| 2019-09-28 12:40:00 | Novel adipokine, FAM19A5, was capable of inhibiting postinjury neointima formation via sphingosine-1-phosphate receptor 2-G12/13-RhoA signaling. | 29453251 |
| 2019-01-19 12:28:00 | sphingosine-1-phosphate receptor (S1PR)2 expressed in pericytes was significantly up-regulated after ischemia in vivo and in vitro. By using a S1PR2 antagonist (JTE-013), we showed that S1PR2 plays a critical role in the induction of BBB permeability of transient middle cerebral artery occlusion (tMCAO) rats and the in vitro BBB model. | 29401609 |
| 2018-01-06 12:50:00 | Sphingosine-1 phosphate (S1P)-mediated activation of S1PR2 plays an important role in regulating intestinal epithelial cell proliferation and migration. S1P significantly upregulated the expression of c-Myc, cyclin D1, E-cadherin and zona occluden-1 (ZO-1), which was completely inhibited by downregulation of S1PR2 expression with a shRNA. | 27814635 |
| Type | IDs |
|---|---|
| Synonymous | Edg5, GPCR18, Gpcr13, H218, snGPCR18 |
| Gene |
UniProtKB-ID:
S1PR2_RAT
UniprotKB:
P47752
UniParc:
UPI000000007D
EMBL:
AF022138,
U10699,
AB016931
Ensembl:
ENSRNOG00000020653
KO:
rno:29415
|
| Nucleutide sequences |
EMBL-CDS:
AAA19241.1,
AAC53494.1,
BAA32454.1
Ensembl_TRS:
ENSRNOT00000028034
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000028034
RefSeq:
NP_058888.1
|
| Others |
UniRef100:
UniRef100_P47752
UniRef90:
UniRef90_P52592
UniRef50:
UniRef50_Q9I8K8
UniGene:
Rn.2491
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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