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2941 GSTA4

2941

GSTA4

glutathione S-transferase alpha 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutathione S-transferase alpha 4

研究结论

Date Results Publications
2017-09-09 10:18:00 These findings demonstrate GSTA4 activation during 4-HNE-induced neoplastic transformation in colorectal carcinogenesis. GSTA4 is a potential surrogate biomarker for CRC screening and should provide novel approaches for chemoprevention. 27065323
2014-03-29 10:08:00 Decreased gene expression of GSTA4 is associated with drug resistance in cervical cancer. 24403508
2013-12-21 11:19:00 Data indicate that steroidogenic factor 1 (SF-1) and glutathione S-transferase A (GSTA) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis. 23650189
2013-05-04 11:43:00 drug resistance in three strains of tumor cells is associated with significant increase in hGSTP1 and hGSTA4 gene expression, whereas increased hGSTK1 gene expression was detected only in resistant erythroleukemia and mammary adenocarcinoma cells. 23330092
2012-04-14 10:48:00 GSTA4 down-regulation and the concomitant increase in 4-hydroxynonenal adducts in muscle are indicative of susceptibility to infection in individuals with severe thermal injuries. 22038048

名称对应

Type IDs
Synonymous GSTA4-4, GTA4
Gene
UniProtKB-ID: GSTA4_HUMAN, A0A024RD58_HUMAN
UniprotKB: O15217, A0A024RD58
UniParc: UPI00001119FD, UPI0000227E23
EMBL: AF025887, AF125271, AF050058, AY878121, BC063439, AF050054, AK315369, CH471081, AF050056, AF050057, AF125272, Y13047, AF050055, AL121969, AF050059, AL162581, BC015523, AF125273, AF020918, CR749474
Ensembl: ENSG00000170899
KO: hsa:2941
Nucleutide sequences
EMBL-CDS: BAG37762.1, CAH18304.1, AAH63439.1, AAD27705.1, AAD27704.1, EAX04394.1, AAD04711.1, EAX04397.1, EAX04395.1, EAX04396.1, AAH15523.1, AAC72706.1, EAX04393.1, AAW56075.1, AAD27706.1, AAC39695.1, CAA73482.1, EAX04399.1
Gene_ORFName: hCG_21940
Ensembl_TRS: ENST00000370963, ENST00000370959, ENST00000370960
Protein sequencees
Ensembl_PRO: ENSP00000359998, ENSP00000359999, ENSP00000360002
RefSeq: XP_005249092.1, NP_001503.1, XP_011512837.1, XP_011512836.1
Others
UniRef100: UniRef100_O15217
UniRef90: UniRef90_O15217
UniRef50: UniRef50_O15217
UniGene: Hs.485557
CCDS: CCDS4948.1

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