| Type | Description |
|---|---|
| Definition | dickkopf WNT signaling pathway inhibitor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 11:20:00 | More surprisingly SOST and DKK1 were overexpressed from day 6 and followed by a dramatic decrease in bone formation from day 8. At the time of arthritis onset, SOST and DKK1 returned to control values, but frizzled related protein 1 (SFRP1), proinflammatory cytokines, and MMPs started to increase. | 29472591 |
| 2018-06-09 10:07:00 | Results suggest that both enhancer of zeste homolog 2 protein (EZH2) and dickkopf-1 protein (Dkk1) might play an essential role in the pathogenesis of hepatic fibrosis. | 28332284 |
| 2017-11-04 11:37:00 | The severity of acute CO poisoning in rat models is associated with elevated serum DKK-1 levels and its upregulation in the brain tissue. | 27353797 |
| 2017-10-14 13:03:00 | Results provide evidence that DKK1 protein is involved in the pathogenesis of tympanosclerosis by regulating the Wnt/beta-catenin signalling pathway. | 28807065 |
| 2017-03-11 11:43:00 | DKK-1 secreted by PMSCs played a vital role in controlling the Wnt/beta-catenin signaling pathway in breast cancer. | 27277008 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
D3Z9J1_RAT
UniprotKB:
D3Z9J1
UniParc:
UPI000017E3E0
EMBL:
AABR07006710,
AABR07006712,
JN966752,
CH473953
Ensembl:
ENSRNOG00000011692,
ENSRNOG00000048688
KO:
rno:108348170,
rno:293897
|
| Nucleutide sequences |
EMBL-CDS:
AFI61655.1,
EDM13121.1
Gene_ORFName:
rCG_48380
Ensembl_TRS:
ENSRNOT00000015771,
ENSRNOT00000074393
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000064286,
ENSRNOP00000015771
RefSeq:
NP_001099820.1
|
| Others |
UniRef100:
UniRef100_D3Z9J1
UniRef90:
UniRef90_O54908
UniRef50:
UniRef50_O54908
UniGene:
Rn.214343
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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