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2938 GSTA1

2938

GSTA1

glutathione S-transferase alpha 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutathione S-transferase alpha 1

研究结论

Date Results Publications
2020-08-15 19:04:00 Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation. 31834435
2020-01-04 11:34:00 GSTA1, GSTM1, and GSTT1 polymorphisms in patients undergoing hematopoietic stem cell transplantation may have affected busulfan pharmacokinetics, but these effects were obscured by other factors, such as underlying disease, systemic conditions, treatment history, and race. 30963629
2019-07-06 11:10:00 Genotypes with lower or null activity of the GSTA1, GSTM1 or GSTT1 did not contribute independently to psoriasis susceptibility in our patients. However, we observed significant associations of genotype combinations with the risk of psoriasis development. 28401601
2019-03-30 12:21:00 For glutathione S-transferase alpha 1(GSTA1) and glutathione S-transferase mu 1(GSTM1) polymorphisms, an association was observed with dietary fiber intake 29087247
2019-02-09 11:47:00 With the use of siRNAs to compare the roles of GSTP1, GSTM2 and GSTA1 in three representative cisplatinresistant solid cancer cells, it is preliminarily concluded that GSTA predominates over the other two isozymes in the cisplatin resistance of the tested lungs, ovaries and stomach cancer cells. 30431119

名称对应

Type IDs
Synonymous GST-epsilon, GST2, GSTA1-1, GTH1
Gene
UniProtKB-ID: GSTA1_HUMAN, A0A140VJK4_HUMAN, B7Z1F9_HUMAN
UniprotKB: P08263, A0A140VJK4, B7Z1F9
UniParc: UPI000013DA34, UPI0001914A89
EMBL: S76235, S76228, AK293371, S76232, BC053578, S76225, CH471081, HM005393, S49975, M14777, M25627, BC110891, M15872, CR407656, S76221, AY532928, M21758, AL590363, S76223
Ensembl: ENSG00000243955
KO: hsa:2938
Nucleutide sequences
EMBL-CDS: AAI10892.1, AAA70226.1, AAA36174.1, AAB24012.1, AAA52618.1, CAG28584.1, EAX04385.1, AAH53578.1, AAT06769.1, AAB20973.1, AAA52615.1, AEE60991.1, BAH11495.1
Ensembl_TRS: ENST00000334575
Protein sequencees
Ensembl_PRO: ENSP00000335620
RefSeq: XP_005249091.1, NP_665683.1, NP_001305988.1
Others
UniRef100: UniRef100_P08263, UniRef100_B7Z1F9
UniRef90: UniRef90_P08263, UniRef90_B7Z1F9
UniRef50: UniRef50_P08263, UniRef50_P00502
UniGene: Hs.446309
CCDS: CCDS4945.1

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