| Type | Description |
|---|---|
| Definition | insulin receptor substrate 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:01:00 | Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats. | 32631952 |
| 2020-10-31 13:15:00 | Imbalanced insulin substrate-1 and insulin substrate-2 signaling trigger hepatic steatosis in vitamin D deficient rats: 8-methoxypsoralen, a vitamin D receptor ligand with a promising anti-steatotic action. | 32045698 |
| 2018-03-03 10:19:00 | a radical increase in the phosphorylation of IRS2 at serine 731 prevents the recruitment of GRB2 adaptor protein which may fail further to connect the Ras and other pathways required to the cell for its survival and to maintain integrity | 28065675 |
| 2017-01-28 10:12:00 | Chronic periapical lesions are associated with decreased insulin signaling - evaluated according to insulin receptor substrate (pp185-insulin receptor substrate 1 [IRS-1]/insulin receptor substrate 2 [IRS-2]) tyrosine phosphorylation status, IRS-1 serine phosphorylation status, and IRS-1 and IRS-2 content - in the skeletal muscle of rats | 26027876 |
| 2016-07-30 11:12:00 | IRS-2 was one of the targets of miR-126. MiR-126 inhibited the beta-cell proliferation through IRS-2 instead of IRS-1. MiR-126 may take part in the glucose homeostasis both through its target IRS-2 and IRS-1. | 26919700 |
| Type | IDs |
|---|---|
| Synonymous | 4PS, IRS-2 |
| Gene |
UniProtKB-ID:
F1MAL5_RAT
UniprotKB:
F1MAL5
UniParc:
UPI0000DA3EAD
EMBL:
AABR07026565,
CH473970
Ensembl:
ENSRNOG00000023509
KO:
rno:29376
|
| Nucleutide sequences |
EMBL-CDS:
EDM08814.1
Gene_ORFName:
rCG_43183
Ensembl_TRS:
ENSRNOT00000032918
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000036862
RefSeq:
NP_001162104.1
|
| Others |
UniRef100:
UniRef100_F1MAL5
UniRef90:
UniRef90_F1MAL5
UniRef50:
UniRef50_Q9Y4H2
UniGene:
Rn.10718
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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