| Type | Description |
|---|---|
| Definition | LDL receptor related protein 5 |
| Date | Results | Publications |
|---|---|---|
| 2013-12-21 10:05:00 | study demonstrates that LRP5/6 mediates pulmonary vascular remodeling and PH in hyperoxia-induced neonatal lung injury | 23481549 |
| 2010-04-19 12:01:00 | Mechanotransduction in osteoblastic cells involves strain-regulated ESRalpha-mediated control of IGFI receptor sensitivity to Ambient IGF, leading to PI3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling | 20042609 |
| 2010-01-21 00:00:00 | 1,25(OH)(2)D(3) can enhance the expression of a critical component of the Wnt signaling pathway which is known to impact osteogenesis | 17229572 |
| 2010-01-21 00:00:00 | Modulation of sclerostin levels appears to be a finely tuned mechanism by which osteocytes coordinate regional and local osteogenesis in response to increased mechanical stimulation, perhaps via releasing the local inhibition of Wnt/Lrp5 signaling | 18089564 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
B2RYI1_RAT
UniprotKB:
B2RYI1
UniParc:
UPI000173E20A
EMBL:
BC166786
KO:
rno:293649
|
| Nucleutide sequences |
EMBL-CDS:
AAI66786.1
|
| Protein sequencees |
RefSeq:
NP_001099791.2,
XP_006230788.1
|
| Others |
UniRef100:
UniRef100_B2RYI1
UniRef90:
UniRef90_O75197
UniRef50:
UniRef50_O75197
UniGene:
Rn.12698
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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