| Type | Description |
|---|---|
| Definition | fatty acid amide hydrolase |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 10:18:00 | Inhibitions of anandamide transport and FAAH synthesis decrease apoptosis and oxidative stress through inhibition of TRPV1 channel in an in vitro seizure model | 30159798 |
| 2018-12-01 12:20:00 | Study examined the effect of URB597, a selective FAAH inhibitor, on neuroinflammation, physiological and behavioural alterations following administration of the TLR3 agonist and viral mimetic poly I:C to female rats. URB597 attenuated TLR3-mediated fever, mechanical and cold allodynia, and anxiety-like behaviour in the elevated plus maze and open field arena; attenuated TLR3-mediated increase in CD11b and CD68 expression. | 29953903 |
| 2018-10-13 12:04:00 | The administration of FAAH inhibitor resulted in increased level of endocannabinoids in kidney of both groups of hypertensive rats led to enhanced expression of the cannabinoid receptors type 1 and 2 in SHR as well as vanilloid receptor 1 receptors in DOCA-salt rats. | 29197803 |
| 2017-12-16 11:08:00 | The hypotensive effect of FAAH inhibitor URB597 is independent of KCa2.3/KCa3.1-endothelium dependent hyperpolarization-type relaxation. | 29038048 |
| 2017-07-01 10:36:00 | This study demonstrates that reduced anandamide content and upregulation of FAAH in the dPAG are associated with hyperalgesia and reduced heart rate sustained weeks after nerve injury. These data provide support for the evaluation of FAAH inhibitors for the treatment of chronic neuropathic pain. | 28148494 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FAAH1_RAT
UniprotKB:
P97612
UniParc:
UPI000012A426
EMBL:
U72497,
BC091148
Ensembl:
ENSRNOG00000011019,
ENSRNOG00000045949
KO:
rno:100911581,
rno:29347
|
| Nucleutide sequences |
EMBL-CDS:
AAB26961.1,
AAH91148.1
Ensembl_TRS:
ENSRNOT00000015667,
ENSRNOT00000015961
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015961,
ENSRNOP00000015667
RefSeq:
NP_077046.1
|
| Others |
UniRef100:
UniRef100_P97612
UniRef90:
UniRef90_P97612
UniRef50:
UniRef50_P97612
UniGene:
Rn.89119
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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