| Type | Description |
|---|---|
| Definition | cofilin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:00:00 | identified cofilin rod, a pathological rod-like aggregation, formed in neurons of in vivo ischemic stroke animal model and induced neuronal impairment. | 29932353 |
| 2020-04-25 11:37:00 | Global inhibition of neddylation in developing neurons leads to cytoskeletal defects, altered actin dynamics and neurite growth impairments, whereas site-specific neddylation of cofilin 1 at K112 regulates neurite outgrowth, suggesting that cofilin 1 neddylation contributes to the regulation of neuronal actin organization. | 32015554 |
| 2020-03-28 11:19:00 | Actin depolymerizing factor (ADF)/cofilin controls actin turnover to sustain axon regeneration after spinal cord injury through its actin-severing activity. This pinpoints ADF/cofilin as a key regulator of axon growth competence, irrespective of developmental stage. | 31400829 |
| 2018-05-26 10:20:00 | CMIP inhibits cofilin1 activity and alters podocyte cytoskeleton organization at least through RhoA signaling in PAinduced podocyte injury | 28791377 |
| 2016-07-30 10:28:00 | cofilin1 is involved in hypertensive nephropathy by modulating the nuclear translocation of NF-kappaB and the expression of its downstream inflammatory factors in renal tubular epithelial cells | 26450610 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
COF1_RAT
UniprotKB:
P45592
UniParc:
UPI0000127E2E
EMBL:
BC059143,
BC086533,
X62908
Ensembl:
ENSRNOG00000020660
KO:
rno:29271
|
| Nucleutide sequences |
EMBL-CDS:
CAA44694.1,
AAH86533.1,
AAH59143.1
Ensembl_TRS:
ENSRNOT00000015962
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000059624
RefSeq:
NP_058843.1
|
| Others |
UniRef100:
UniRef100_P45592
UniRef90:
UniRef90_P45592
UniRef50:
UniRef50_P45592
UniGene:
Rn.11675
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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