| Type | Description |
|---|---|
| Definition | monoamine oxidase A |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension. | 33264068 |
| 2019-03-02 10:07:00 | MAO-A is induced in diabetic aortas and vitamin D can improve diabetes-induced endothelial dysfunction by modulating the MAO-A expression. | 30167938 |
| 2018-09-22 11:36:00 | Acute alcohol withdrawal was associated with elevated MAO-A levels and activity in the brain. | 29549852 |
| 2018-07-14 10:43:00 | These results suggest that the inhibition of Sirt1/MAO-A expression in astrocytes in the prefrontal cortex may contribute to the different anti-depressive effects of Repetitive transcranial magnetic stimulation with different parameters, and may also provide a novel insight into the mechanisms underlying major depressive disorder. | 28948423 |
| 2018-02-03 12:02:00 | Extensive SAR studies and in vivo behavioral evaluations of this and other related analogue series identified a number of potential clinical development candidates; ultimately, compound 8f was identified as a candidate molecule with high selectivity toward MAO-B (29-56 nM) over MAO-A (19% inhibition at a screening concentration of 50 muM), an excellent profile against a panel of other enzymes and receptors, good pharma... | 28857544 |
| Type | IDs |
|---|---|
| Synonymous | Mao |
| Gene |
UniProtKB-ID:
G3V9Z3_RAT
UniprotKB:
G3V9Z3
UniParc:
UPI000019B716
EMBL:
AABR07036901,
CH474009
Ensembl:
ENSRNOG00000002848
KO:
rno:29253
|
| Nucleutide sequences |
EMBL-CDS:
EDL97663.1
Gene_ORFName:
rCG_42932
Ensembl_TRS:
ENSRNOT00000066674
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000063784
RefSeq:
NP_387502.1
|
| Others |
UniRef100:
UniRef100_G3V9Z3
UniRef90:
UniRef90_G3V9Z3
UniRef50:
UniRef50_P21397
UniGene:
Rn.224544
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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