| Type | Description |
|---|---|
| Definition | coagulation factor II |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 10:26:00 | These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes. | 28489922 |
| 2017-04-08 11:36:00 | Study suggests a potent role for spinal thrombin and its activation of PAR1 in pain onset following neuropathic injury | 28059686 |
| 2015-04-11 13:30:00 | Inflammatory bowel disease is associated with production of prothrombin in the dorsal motor nucleus of the vagus (DMV). Thrombin in the DMV causes vagal neuron apoptosis and decreased sensitivity to neurotransmitters. | 24916589 |
| 2013-07-13 11:13:00 | Thrombin-induced overexpression of TGF-beta1 and activation of its downstream factors might be a mechanism of communicating hydrocephalus after subarachnoid hemorrhage. | 23338707 |
| 2013-06-01 12:42:00 | These results suggest that thrombin triggers the generation of epileptic seizures by reducing the inhibitory and increasing the excitatory tone in CA3 neurons | 23103417 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G3V843_RAT
UniprotKB:
G3V843
UniParc:
UPI000019BF84
EMBL:
CH473949,
AABR07052881
Ensembl:
ENSRNOG00000016325
KO:
rno:29251
|
| Nucleutide sequences |
EMBL-CDS:
EDL79531.1
Gene_ORFName:
rCG_27251
Ensembl_TRS:
ENSRNOT00000022233
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000022233
RefSeq:
NP_075213.2
|
| Others |
UniRef100:
UniRef100_G3V843
UniRef90:
UniRef90_P19221
UniRef50:
UniRef50_P00734
UniGene:
Rn.54498
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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