| Type | Description |
|---|---|
| Definition | dopamine receptor D3 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:15:00 | Differential effects of D-cycloserine and amantadine on motor behavior and D2/3 receptor binding in the nigrostriatal and mesolimbic system of the adult rat. | 31695055 |
| 2020-04-18 11:14:00 | Autoradiography revealed an increased expression of D3R in 14-day-old Genetic Absence Epilepsy Rats From Strasbourg, before absence seizure onset, that persists in adulthood, as compared to age-matched non-epileptic controls. | 31535376 |
| 2019-11-23 12:24:00 | Study confirms the 5alpha-reductase enzyme as a potential therapeutic target for treatment of dyskinesia in Parkinson's disease, suggesting the first ever evidence that neurosteroidogenesis may affect functional interaction between dopamine D1R and D3R. | 30261284 |
| 2019-03-23 10:23:00 | Study showed that while dopamine d2 receptor antagonism blocked, dopamine d3 receptor antagonism failed to impair cocaine-primed relapse. | 30489132 |
| 2019-02-16 12:29:00 | D3R knockout (D3R(-/-)) mice displayed decreased freezing time of contextual fearing and anxiolytic effects following training sessions consisting of exposure to inescapable electric foot-shocks. Similarly, highly selective blockade of D3Rs by YQA14, a novel D3R antagonist, significantly ameliorated freezing and anxiogenic-like behaviours in the single-prolonged stress model of post-traumatic stress disorder in rats. | 29510167 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DRD3_RAT
UniprotKB:
P19020
UniParc:
UPI000002CB23,
UPI000002A7AC,
UPI000002A7AB
EMBL:
M69193,
M69191,
S63847,
M69194,
M69190,
X53944,
M69189,
S63846,
M69192
Ensembl:
ENSRNOG00000060806
KO:
rno:29238
|
| Nucleutide sequences |
EMBL-CDS:
AAB27545.1,
CAA37887.1,
AAA41076.1
Ensembl_TRS:
ENSRNOT00000089057
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073117
RefSeq:
NP_058836.1,
XP_006248375.2
|
| Others |
UniRef100:
UniRef100_P19020
UniRef90:
UniRef90_P19020
UniRef50:
UniRef50_P35462
UniGene:
Rn.10356
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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