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291912 Nod2

291912

Nod2

nucleotide-binding oligomerization domain containing 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition nucleotide-binding oligomerization domain containing 2

研究结论

Date Results Publications
2018-10-06 12:17:00 Data show that mRNA expression and protein levels of nucleotide-binding oligomerization domain-containing proteins (NOD1, NOD2) and NLR family, pyrin domain containing 3 protein (NLRP3) were significantly increased in the severe acute pancreatitis (SAP) models. 29303910
2018-08-18 11:42:00 NOD2 could play a role in intestinal pathophysiology not only through its inherent innate immune role but also due to its interaction with other receptors as TLR2 and the modulation of the intestinal serotonergic system decreasing SERT activity and expression. 29913461
2016-02-20 11:14:00 in rat peritoneal mast cells the ingested cargo can, through interruptions of the phagosome membrane, interact directly with NOD1 and NOD2 proteins, which act as switches in the process of cytokine production. 25502289
2016-02-06 11:46:00 Nod2-Rip2-NFkappaB signaling involved in the small intestinal inflammatory injury caused by muramyl dipeptide which is transported through PepT1. 26138652
2016-02-06 10:11:00 Mammary innate immune responses were activated after Staphylococcus aureus inoculation. TLR2, NOD2, and inflammatory cytokines (TNF-alpha, IL-1beta, IL-6, CXCL1, IL-10, TGF-beta1, and IFN-gamma) are involved in the response to mastitis induced by S. aureus. 25990971

名称对应

Type IDs
Synonymous Card15
Gene
UniProtKB-ID: D4A5W3_RAT
UniprotKB: D4A5W3
UniParc: UPI000155261C
EMBL: CH474037, AABR07043075, AABR07043076
Ensembl: ENSRNOG00000014124
KO: rno:291912
Nucleutide sequences
EMBL-CDS: EDL87529.1
Gene_ORFName: rCG_63140
Ensembl_TRS: ENSRNOT00000065103
Protein sequencees
Ensembl_PRO: ENSRNOP00000061463
RefSeq: XP_017456696.1, XP_008770594.1, XP_008770595.1, NP_001099642.1, XP_008770593.1
Others
UniRef100: UniRef100_A0A0G2K4Z7
UniRef90: UniRef90_A0A0G2K4Z7
UniRef50: UniRef50_Q8K3Z0
UniGene: Rn.218600

全选

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