| Type | Description |
|---|---|
| Definition | FTO, alpha-ketoglutarate dependent dioxygenase |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 11:49:00 | Silencing of FTO expression, but not ARL15, inhibits insulin secretion by affecting metabolic signaling. | 29890211 |
| 2019-03-30 11:10:00 | Study found the amount of the fat mass/obesity-associated protein (FTO) protein increased in obese rats, while FTO and neuropeptide Y levels decreased in the groups treated with topiramate. The mechanism of the effect of topiramate to create a state of obesity is thought to involve the decrease in the levels of NPY and FTO. | 28914170 |
| 2017-03-18 11:14:00 | Study revealed that diet was an important factor modulating transcription of Fto and Irx3, but its effect is time-dependent. In contrast, the DNA methylation profiles of Fto and Irx3 were not altered by nutrition, which may indicate that the feeding type, when applied postnatally, did not affect DNA methylation of these genes. | 28179100 |
| 2014-05-17 10:29:00 | demonstrates leptin-induced FTO upregulation in cardiomyocytes via dependent CUX1 upregulation and suggests an FTO regulatory function of leptin | 24019958 |
| 2013-12-21 11:19:00 | Both Fto mRNA and catechol-O-methyltransferaze mRNA are upregulated in an identical time-dependent manner in fasting animals. | 23671692 |
| Type | IDs |
|---|---|
| Synonymous | RGD1305121 |
| Gene |
UniProtKB-ID:
FTO_RAT,
B4F7E0_RAT
UniprotKB:
Q2A121,
B4F7E0
UniParc:
UPI0000502382
EMBL:
BC168239,
AM233906
Ensembl:
ENSRNOG00000011728
KO:
rno:291905
|
| Nucleutide sequences |
EMBL-CDS:
CAJ80872.1,
AAI68239.1
Ensembl_TRS:
ENSRNOT00000015718
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015718
RefSeq:
NP_001034802.1
|
| Others |
UniRef100:
UniRef100_Q2A121
UniRef90:
UniRef90_Q8BGW1
UniRef50:
UniRef50_Q8BGW1
UniGene:
Rn.229320
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员