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2918 GRM8

2918

GRM8

glutamate metabotropic receptor 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate metabotropic receptor 8

研究结论

Date Results Publications
2021-02-02 13:24:00 GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task. 32299001
2019-11-09 12:32:00 Transcriptional activation of GRM8 lung squamous cell carcinoma tumor cells induced cell proliferation by inhibiting cAMP pathway and activating MAPK pathway. 30391781
2019-04-27 10:16:00 rs712723 in GRM8 was selected for genotyping. The allele C and genotype CC (allele C: OR 1.48, 95% CI 1.13-1.94; genotype CC: OR 1.71, 95% CI 1.09-2.68) of rs712723 polymorphism was found to have a significant association with risk of schizophrenia while allele T (P = 0.003) and genotype TT (P = 0.028) frequencies were found lower in control patients. 30288643
2017-08-26 12:18:00 This study showed that GRM8 was nominally associated (p < 0.05) with both delta measures (energy and intertrial phase coherence). 27871913
2016-10-29 11:05:00 Study represents a genetic association test towards single variant and multi-markers interaction of GRM7 and GRM8 genes in both schizophrenia and major depressive disorders in Han Chinese population 26655190

名称对应

Type IDs
Synonymous GLUR8, GPRC1H, MGLUR8, mGlu8
Gene
UniProtKB-ID: GRM8_HUMAN
UniprotKB: O00222
UniParc: UPI000012F085, UPI000002ADF3, UPI000002ADF2
EMBL: BC101675, EU432125, BC093725, EU368948, U92459, U95025, CH236947, AJ236922, AJ236921, AY608335
Ensembl: ENSG00000179603
KO: hsa:2918
Nucleutide sequences
EMBL-CDS: AAT37959.1, ABY87924.1, AAH93725.1, AAB51764.1, EAL24322.1, CAB36969.1, CAB36968.1, AAB72040.1, ABY59657.1, AAI01676.1
Ensembl_TRS: ENST00000341617, ENST00000472701, ENST00000358373, ENST00000339582
Protein sequencees
Ensembl_PRO: ENSP00000351142, ENSP00000345747, ENSP00000344173, ENSP00000419832
RefSeq: XP_011514405.1, NP_000836.2, XP_011514410.1, XP_016867567.1, XP_016867564.1, NP_001358016.1, NP_001358012.1, NP_001358017.1, XP_011514403.1, NP_001120795.1, XP_016867565.1, XP_016867569.1, XP_011514396.1, XP_016867566.1, XP_011514397.1, NP_001358013.1, XP_024302504.1, NP_001358015.1, XP_011514404.1, XP_016867568.1, NP_001358014.1
Others
UniRef100: UniRef100_O00222
UniRef90: UniRef90_O00222
UniRef50: UniRef50_O00222
UniGene: Hs.449625
CCDS: CCDS47696.1, CCDS5794.1

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