Rit2 - Ras-like without CAAX 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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291713 Rit2

基因描述

Type	Description
Definition	Ras-like without CAAX 2

研究结论

Date	Results	Publications
2011-07-28 16:08:00	observations establish Rin as a neuronal specific regulator of neurotrophin signaling, required to couple NGF stimulation to sustain activation of p38 MAP kinase and b-Raf signaling cascades required for neuronal development [rin]	16157584
2010-08-26 12:32:00	These observations identify an unsuspected role for Rin in neuronal PACAP signaling and establish a novel Galpha-Src-Rin-HSP27 signal transduction pathway as a critical element in PACAP38-mediated neuronal differentiation signaling.	18541665
2010-01-21 00:00:00	Rit is a convergence point for multiple signaling pathways and it functions to promote axonal growth but inhibit dendritic growth via activation of ERK1/2	17460085

名称对应

Type	IDs
Synonymous	Rin, Rit1
Gene	UniProtKB-ID: RIT2_RAT UniprotKB: Q5BJQ5 UniParc: UPI0000029BF2 EMBL: BC091382 Ensembl: ENSRNOG00000017568 KO: rno:291713
Nucleutide sequences	EMBL-CDS: AAH91382.1 Ensembl_TRS: ENSRNOT00000023874
Protein sequencees	Ensembl_PRO: ENSRNOP00000023871 RefSeq: NP_001013078.1
Others	UniRef100: UniRef100_Q5BJQ5 UniRef90: UniRef90_P70425 UniRef50: UniRef50_P70425 UniGene: Rn.106719

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
23805044	RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol. Vis. Ling Zhang , Karl Wahlin , Yuanyuan Li , Tomohiro Masuda , Zhiyong Yang , Donald J Zack , Noriko Esumi	2013-01-01	Rit2, RIT2
21957239	The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter trafficking. J Neurosci Deanna M Navaroli , Zachary H Stevens , Zeljko Uzelac , Luke Gabriel , Michael J King , Lawrence M Lifshitz , Harald H Sitte , Haley E Melikian	2011-09-28	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18541665	Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation. Mol. Cell. Biol. Geng-Xian Shi , Ling Jin , Douglas A Andres	2008-08-01	Rit2, Src, Adcyap1, Hspb1, Rit2, Src
17460085	The novel GTPase Rit differentially regulates axonal and dendritic growth. J. Neurosci. Pamela J Lein , Xin Guo , Geng-Xian Shi , Melissa Moholt-Siebert , Donald Bruun , Douglas A Andres	2007-04-25	Rit2
16157584	Rin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiation. J Biol Chem Geng-Xian Shi , Jiahuai Han , Douglas A Andres	2005-11-11	-
16122393	Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin. BMC Neurosci Christine Hartwig , Andres Veske , Sarka Krejcova , Georg Rosenberger , Ulrich Finckh	2005-01-01	Plxnb3, Rit2, PLXNB3, RIT2
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7
14662747	Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells. J. Cell Biol. Mitsunobu Hoshino , Shun Nakamura	2003-12-08	Cdc42
12934100	Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor. Oncogene M Calissano , D S Latchman	2003-08-21	-

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