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2917 GRM7

2917

GRM7

glutamate metabotropic receptor 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate metabotropic receptor 7

研究结论

Date Results Publications
2020-12-19 13:42:00 GRM7 polymorphisms are not associated with ischemic stroke in Iranian population. 32011203
2020-05-16 11:56:00 frequency of A allele of the rs779867 OF grm7 was significantly lower in the schizophrenic patients compared with healthy subjects (OR (95% CI) = 0.71 (0.56-0.89), adjusted P value = 0.008) 30610437
2020-05-16 11:38:00 There were no significant differences in genotype, allele and haplotypes frequencies of the GRM7 rs6782011 and rs779867 between bipolar disorder 1 (BPD1) patients and controls. The CC genotype of the rs6782011 was significantly associated with BPD2 in a recessive model and with ADHD in dominant and co-dominant models.The C G haplotype was more prevalent among both BPD2 patients and MDD patients. 31170425
2020-04-04 12:16:00 revealed significant interethnic differences in allele polymorphisms of NAT2, GRM7 and GRHL2 exhibit quite marked ethnic differences in Roma populations 29455378
2020-02-15 13:07:00 These findings provide a model in which Nedd4 and beta-arrestin act together as a complex to regulate mGlu7 surface expression and function at presynaptic terminals. 31373553

名称对应

Type IDs
Synonymous GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87
Gene
UniProtKB-ID: GRM7_HUMAN, B2R693_HUMAN, Q59G95_HUMAN, B9EGG9_HUMAN
UniprotKB: Q14831, B2R693, Q59G95, B9EGG9
UniParc: UPI000006DEFA, UPI0001EC9644, UPI00017505A2, UPI000192C3EF, UPI0000071950, UPI00004F6BF5, UPI000004A7E4, UPI000004A7E3
EMBL: AB209214, AF458054, BC136459, AF458053, U92458, AF458052, X94552, AK312488
Ensembl: ENSG00000196277
KO: hsa:2917
Nucleutide sequences
EMBL-CDS: AAM47559.1, AAM47558.1, CAA64245.1, AAB51763.1, AAM47557.1, BAG35390.1, BAD92451.1, AAI36460.1
Ensembl_TRS: ENST00000467425, ENST00000389335, ENST00000389336, ENST00000357716, ENST00000486284
Protein sequencees
Ensembl_PRO: ENSP00000419835, ENSP00000373986, ENSP00000373987, ENSP00000417536, ENSP00000350348
RefSeq: XP_016861761.1, XP_024309263.1, XP_024309261.1, NP_870989.1, XP_024309265.1, XP_024309266.1, XP_016861762.1, XP_024309260.1, NP_000835.1, XP_024309262.1
Others
UniRef100: UniRef100_B9EGG9, UniRef100_Q14831, UniRef100_Q59G95, UniRef100_B2R693
UniRef90: UniRef90_Q5RDQ8, UniRef90_P35400, UniRef90_A0A452UZP7
UniRef50: UniRef50_P35400, UniRef50_Q5RDQ8, UniRef50_A0A452UZP7
UniGene: Hs.606393, Hs.660131
CCDS: CCDS43042.1

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