例如:"NBL1", "4681", "drought"
收藏
29153 Capn1

29153

Capn1

calpain 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition calpain 1

研究结论

Date Results Publications
2020-07-25 10:14:00 elevated ammonia level may induce neuronal dysfunction via abnormal calcium influx and calpain-dependent CRMP-2 cleavage 31278888
2020-05-30 12:10:00 In sum, by up- and down-regulating the persistent sodium current and KCC2, the calpain-mediated proteolysis of voltage-gated sodium (Nav) channels and KCC2 drives the hyperexcitability of motoneurons which leads to spasticity after spasticity after spinal cord injury. 31815668
2020-02-08 10:34:00 The data support a link between Parkin phosphorylation and its cleavage by calpain. 30796971
2019-12-28 11:34:00 Study found that the number of spontaneous seizures detected prior to sample collection was correlated with altered calpain activity and expression. 30423475
2019-02-23 12:18:00 Results implicate calpain-2 in the Ca2+-dependent regulation of extrasynaptic NMDARs and calpain-1 in the Ca2+-dependent regulation of synaptic NMDARs in substantia nigra pars compacta-dopaminergic neurons during the first postnatal week and suggest that these roles of calpain-1 and calpain-2 are developmentally regulated. 29772491

名称对应

Type IDs
Gene
UniProtKB-ID: CAN1_RAT, F1LS29_RAT
UniprotKB: P97571, F1LS29
UniParc: UPI0001B7C06F, UPI0000126E94
EMBL: BC061880, AC131475, U53858
Ensembl: ENSRNOG00000020935
KO: rno:29153
Nucleutide sequences
EMBL-CDS: AAC53001.1, AAH61880.1
Ensembl_TRS: ENSRNOT00000028431
Protein sequencees
Ensembl_PRO: ENSRNOP00000028431
RefSeq: NP_062025.1, XP_008758310.1, XP_008758311.1, XP_006230768.1
Others
UniRef100: UniRef100_F1LS29, UniRef100_P97571
UniRef90: UniRef90_O35350, UniRef90_P97571
UniRef50: UniRef50_P97571, UniRef50_O35350
UniGene: Rn.6037

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员