| Type | Description |
|---|---|
| Definition | calnexin |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:48:00 | The authors demonstrate that the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) missense mutation located in the Cav3.2 III-IV linker alters the Cav3.2/calnexin interaction, resulting in an increased surface expression of the channel and a concomitant elevation in calcium influx. | 28912545 |
| 2019-06-29 10:38:00 | The mechanism underlying these effects may involve the direct binding of PPARgamma to the pre-miR-711 promoter for the upregulation of miR-711, which may induce ER stress-mediated cardiomyocyte apoptosis via calnexin. | 29522763 |
| 2017-05-27 10:55:00 | Therefore, these results indicate that obesity down-regulates CNX and CRT expressions and their activities and diabetes up-regulates the expressions and activities of CNX and CRT. Our findings clearly suggest that metabolic syndrome affects the lectin-like chaperones in the CNX/CRT cycle at both the activity and expression levels. | 27425249 |
| 2014-04-12 12:00:00 | calnexin localizes to the neuronal cell membrane & this recruitment is regulated in an NMDA receptor-dependent manner. immunoisolation of vesicles revealed co-localization of GluA2 and calnexin in post-ER intracellular membrane components. | 23851254 |
| 2010-11-27 10:09:00 | Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation | 20720009 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CALX_RAT
UniprotKB:
P35565
UniParc:
UPI0000126E83
EMBL:
L18889
Ensembl:
ENSRNOG00000003343
KO:
rno:29144
|
| Nucleutide sequences |
EMBL-CDS:
AAA21015.1
Ensembl_TRS:
ENSRNOT00000049942
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000040859
RefSeq:
XP_008765902.1,
NP_742005.1,
XP_008765901.1
|
| Others |
UniRef100:
UniRef100_P35565
UniRef90:
UniRef90_P35565
UniRef50:
UniRef50_P27824
UniGene:
Rn.1762
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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